Comparison between Self-Report and a Dipstick Method (NicCheck 1) to Assess Nicotine Intake

C.M. Bernaards, J.W. Twisk, W. van Mechelen, J. Snel, H.C. Kemper

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23 Citations (Scopus)


The purpose of this study was to investigate the agreement between self-reported tobacco consumption and NicCheck 1 (Dynagen Inc. Cambridge, Mass., USA) regarding smoking status and nicotine intake in a population of smokers (20.8%) and non-smokers. NicCheck 1 is a dipstick that changes colour in the presence of urinary nicotine metabolites. Smoking was assessed by self-report and NicCheck 1 in 169 males and 191 females (mean age 36.0 SD 0.7). Self-report and NicCheck 1 agreed highly on smoking status, especially in moderate to heavy smokers. With regard to nicotine intake, there was a large overlap in self-reported tobacco consumption between NicCheck 1 levels, despite a relatively high correlation coefficient between self-report and NicCheck 1 in smokers (i.e. 0.74). No effect modification by gender or BMI was found. When both methods were validated against two blood lipid parameters, self-report seemed to do equally well as NicCheck 1 in assessing nicotine intake.

Original languageUndefined/Unknown
Pages (from-to)163-167
Number of pages5
JournalEuropean Addiction Research
Issue number4
Publication statusPublished - 2004


  • Adult
  • Cholesterol, HDL/blood
  • Cholesterol/blood
  • Cohort Studies
  • Colorimetry
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Netherlands
  • Nicotine/administration & dosage
  • Predictive Value of Tests
  • Reagent Strips
  • Self Disclosure
  • Smoking/urine
  • Statistics as Topic
  • Tobacco Use Disorder/diagnosis

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