Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue

Paul J. M. Wijnker; Felix W. Friedrich; Alexander Dutsch; Silke Reischmann; Alexandra Eder; Ingra Mannhardt; Giulia Mearini; Thomas Eschenhagen; Jolanda van der Velden; Lucie Carrier

doi:https://doi.org/10.1016/j.yjmcc.2016.03.003

Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue

Paul J. M. Wijnker, Felix W. Friedrich, Alexander Dutsch, Silke Reischmann, Alexandra Eder, Ingra Mannhardt, Giulia Mearini, Thomas Eschenhagen, Jolanda van der Velden, Lucie Carrier

Physiology (VUmc)

Research output: Contribution to journal › Article › Academic › peer-review

44 Citations (Scopus)

Original language	English
Pages (from-to)	82-92
Journal	Journal of molecular and cellular cardiology
Volume	97
DOIs	https://doi.org/10.1016/j.yjmcc.2016.03.003
Publication status	Published - Aug 2016

Keywords

Cardiac myosin-binding protein-C
Engineered heart tissue
Haploinsufficiency
Hypertrophic cardiomyopathy
Missense mutation
Truncating mutation

Access to Document

https://doi.org/10.1016/j.yjmcc.2016.03.003

Cite this

Wijnker, P. J. M., Friedrich, F. W., Dutsch, A., Reischmann, S., Eder, A., Mannhardt, I., Mearini, G., Eschenhagen, T., van der Velden, J., & Carrier, L. (2016). Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue. Journal of molecular and cellular cardiology, 97, 82-92. https://doi.org/10.1016/j.yjmcc.2016.03.003

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keywords = "Cardiac myosin-binding protein-C, Engineered heart tissue, Haploinsufficiency, Hypertrophic cardiomyopathy, Missense mutation, Truncating mutation",

author = "Wijnker, {Paul J. M.} and Friedrich, {Felix W.} and Alexander Dutsch and Silke Reischmann and Alexandra Eder and Ingra Mannhardt and Giulia Mearini and Thomas Eschenhagen and {van der Velden}, Jolanda and Lucie Carrier",

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Wijnker, PJM, Friedrich, FW, Dutsch, A, Reischmann, S, Eder, A, Mannhardt, I, Mearini, G, Eschenhagen, T, van der Velden, J & Carrier, L 2016, 'Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue', Journal of molecular and cellular cardiology, vol. 97, pp. 82-92. https://doi.org/10.1016/j.yjmcc.2016.03.003

TY - JOUR

T1 - Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue

AU - Wijnker, Paul J. M.

AU - Friedrich, Felix W.

AU - Dutsch, Alexander

AU - Reischmann, Silke

AU - Eder, Alexandra

AU - Mannhardt, Ingra

AU - Mearini, Giulia

AU - Eschenhagen, Thomas

AU - van der Velden, Jolanda

AU - Carrier, Lucie

PY - 2016/8

Y1 - 2016/8

KW - Cardiac myosin-binding protein-C

KW - Engineered heart tissue

KW - Haploinsufficiency

KW - Hypertrophic cardiomyopathy

KW - Missense mutation

KW - Truncating mutation

U2 - https://doi.org/10.1016/j.yjmcc.2016.03.003

DO - https://doi.org/10.1016/j.yjmcc.2016.03.003

M3 - Article

C2 - 27108529

SN - 0022-2828

VL - 97

SP - 82

EP - 92

JO - Journal of molecular and cellular cardiology

JF - Journal of molecular and cellular cardiology

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