TY - GEN
T1 - Computational analysis of calcium transients in the intact rat heart; model identification
AU - Van Riel, N. A.W.
AU - van der Vusse, Ger J.
N1 - Copyright: Copyright 2004 Elsevier Science B.V., Amsterdam. All rights reserved.
PY - 2002
Y1 - 2002
N2 - The sarcoplasmic calcium transients determine the contraction strength during the cardiac cycle. A computational model has been derived that can be uniquely identified based on the available time series data of the free calcium concentration in the sarcoplasm. The model assesses the quantitatively most important processes in calcium handling in the intact heart at an integral system level. The in vivo kinetic parameters of cardiac calcium handling have been analyzed.
AB - The sarcoplasmic calcium transients determine the contraction strength during the cardiac cycle. A computational model has been derived that can be uniquely identified based on the available time series data of the free calcium concentration in the sarcoplasm. The model assesses the quantitatively most important processes in calcium handling in the intact heart at an integral system level. The in vivo kinetic parameters of cardiac calcium handling have been analyzed.
UR - http://www.scopus.com/inward/record.url?scp=0036994620&partnerID=8YFLogxK
M3 - Conference contribution
VL - 3
T3 - Proceedings of the IEEE Conference on Decision and Control
SP - 2536
EP - 2537
BT - Proceedings of the IEEE Conference on Decision and Control
T2 - 41st IEEE Conference on Decision and Control
Y2 - 10 December 2002 through 13 December 2002
ER -