TY - JOUR
T1 - Consequences of diagnosing a tumor predisposition syndrome in children with cancer: A literature review
AU - Postema, Floor A. M.
AU - Hopman, Saskia M. J.
AU - Hennekam, Raoul C.
AU - Merks, Johannes H. M.
PY - 2018
Y1 - 2018
N2 - Up to 8.5% of children with cancer have a genetic cause for their cancer: a tumor predisposition syndrome (TPS). Diagnosing a TPS is of great importance, as it may have major consequences for clinical care. Patients with TPSs require specific monitoring and management. We present an overview of the cancer-related and noncancer-related consequences for the 36 most common TPSs.
AB - Up to 8.5% of children with cancer have a genetic cause for their cancer: a tumor predisposition syndrome (TPS). Diagnosing a TPS is of great importance, as it may have major consequences for clinical care. Patients with TPSs require specific monitoring and management. We present an overview of the cancer-related and noncancer-related consequences for the 36 most common TPSs.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85035017689&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/28834056
U2 - https://doi.org/10.1002/pbc.26718
DO - https://doi.org/10.1002/pbc.26718
M3 - Review article
C2 - 28834056
SN - 1545-5009
VL - 65
JO - Pediatric Blood and Cancer
JF - Pediatric Blood and Cancer
IS - 1
M1 - e26718
ER -