Contact allergy to diazolidinyl urea (Germall II®)

Anton C. de Groot, Dere P. Bruynzeel, Berend A. Jagtman, J. Willem Weyland

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Abstract

4 cases of contact allergy to diazolidinyl urea (Germall II®) in a “hypoallergenic” brand of cosmetics are described, 2 patients sensitized by these cosmetics were not allergic to formaldehyde. 2 oilier patients already sensitive to formaldehyde had exacerbations of dermatitis due to diazolidinyl urea. The following tentative conclusions were drawn, (i) Contact allergy to diazolidinyl urea may or may not he due to formaldehyde sensitivity, (ii) Patients allergic to formaldehyde may suffer contact allergic reactions from the use of cosmetics containing diazolidinyl urea, (iii) Patients sensitised to diazolidinyl urea may cross‐react to imidazolidinyl urea and vice‐versa, (iv) It is suggested that the sensitizing potential of diazolidinyl urea is greater than that of imidazolidinyl urea, (v) Aq. solutions may be preferable to pet. for patch testing with diazolidinyl urea. Copyright © 1988, Wiley Blackwell. All rights reserved
Original languageEnglish
Pages (from-to)202-205
JournalContact dermatitis
Volume18
Issue number4
DOIs
Publication statusPublished - 1988
Externally publishedYes

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