Controlling immunity at dendritic cell and T cell level by host, pathogens, and as therapeutics

L.E.H. van der Donk

Controlling immunity at dendritic cell and T cell level by host, pathogens, and as therapeutics

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

A balance between immune activation and inhibition is essential to attack and eliminate pathogens whilst protecting against harmful effects on the host. To prevent ineffective or excessive immune responses, activation of dendritic cells (DCs) and T cells is controlled at different levels. Here, we have investigated how the host as well as pathogens affect immune responses by DCs and T cells

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	Geijtenbeek, Theo, Supervisor Ates, Louis, Co-supervisor Bermejo-Jambrina, Marta, Co-supervisor Geijtenbeek, T.B.H., Supervisor, External person
Award date	25 Oct 2023
Print ISBNs	9789464198508
Publication status	Published - 2023

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abstract = "A balance between immune activation and inhibition is essential to attack and eliminate pathogens whilst protecting against harmful effects on the host. To prevent ineffective or excessive immune responses, activation of dendritic cells (DCs) and T cells is controlled at different levels. Here, we have investigated how the host as well as pathogens affect immune responses by DCs and T cells",

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AU - van der Donk, L.E.H.

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N2 - A balance between immune activation and inhibition is essential to attack and eliminate pathogens whilst protecting against harmful effects on the host. To prevent ineffective or excessive immune responses, activation of dendritic cells (DCs) and T cells is controlled at different levels. Here, we have investigated how the host as well as pathogens affect immune responses by DCs and T cells

AB - A balance between immune activation and inhibition is essential to attack and eliminate pathogens whilst protecting against harmful effects on the host. To prevent ineffective or excessive immune responses, activation of dendritic cells (DCs) and T cells is controlled at different levels. Here, we have investigated how the host as well as pathogens affect immune responses by DCs and T cells

UR - https://pure.uva.nl/ws/files/140914677/Licentieovereenkomst_medeondertekend_.pdf

M3 - Phd-Thesis - Research and graduation internal

SN - 9789464198508

ER -

Controlling immunity at dendritic cell and T cell level by host, pathogens, and as therapeutics

Abstract

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