TY - JOUR
T1 - Cost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective
AU - Rintoul, Robert C.
AU - Glover, Matthew J.
AU - Jackson, Christopher
AU - Hughes, Victoria
AU - Tournoy, Kurt G.
AU - Dooms, Christophe
AU - Annema, Jouke T.
AU - Sharples, Linda D.
PY - 2014
Y1 - 2014
N2 - In the ASTER study, mediastinal staging was more accurate for patients randomised to combined endobronchial and endoscopic ultrasound, followed by surgical staging if endoscopy was negative, versus surgical staging alone. Here, we report survival, quality of life and cost effectiveness up to 6 months, for the UK, The Netherlands and Belgium, separately. Survival in the two arms of the study was similar. In all three countries, the endosonography strategy had slightly higher quality-adjusted life years over 6 months, and was cheaper. Therefore, based on clinical accuracy and cost effectiveness, we conclude that mediastinal staging should commence with endosonography
AB - In the ASTER study, mediastinal staging was more accurate for patients randomised to combined endobronchial and endoscopic ultrasound, followed by surgical staging if endoscopy was negative, versus surgical staging alone. Here, we report survival, quality of life and cost effectiveness up to 6 months, for the UK, The Netherlands and Belgium, separately. Survival in the two arms of the study was similar. In all three countries, the endosonography strategy had slightly higher quality-adjusted life years over 6 months, and was cheaper. Therefore, based on clinical accuracy and cost effectiveness, we conclude that mediastinal staging should commence with endosonography
U2 - https://doi.org/10.1136/thoraxjnl-2013-204374
DO - https://doi.org/10.1136/thoraxjnl-2013-204374
M3 - Article
C2 - 24064440
SN - 0040-6376
VL - 69
SP - 679
EP - 681
JO - Thorax
JF - Thorax
IS - 7
ER -