TY - JOUR
T1 - Cross-sectional and Longitudinal Relationships between Perceived Stress and C-reactive Protein in Men and Women.
AU - Barbosa-Leiker, C.
AU - Roper, V.
AU - McPherson, S.
AU - Lei, M.
AU - Wright, B.
AU - Hoekstra, T.
AU - Kostick, M.
PY - 2014
Y1 - 2014
N2 - To date, an examination of the longitudinal relationship between perceived stress and C-reactive protein (CRP) is limited. We explored the relationship between perceived stress and CRP concurrently and across 2 and 4years in 383 men and women. Multiple linear regressions examined the cross-sectional and longitudinal relationships between baseline stress and counter-stress scores with CRP at baseline, 2years after baseline and 4years after baseline, while controlling for covariates (age, smoking status, anti-inflammatory use, oral contraceptive use, physical activity, menopausal status, years since onset of menopause, post-menopausal hormone use and body mass index). Results indicate that stress and counter-stress were not related to CRP in either men or women at study baseline or 2years later. Across a 4-year time frame, higher stress values were related to higher CRP values in women, but not men. Counter-stress was not related to CRP values in men or women across the 4years. This study highlights the importance of examining the cross-sectional and longitudinal relationship between perceived stress and inflammation separately in men and women. Copyright © 2013 John Wiley & Sons, Ltd. © 2013 John Wiley & Sons, Ltd.
AB - To date, an examination of the longitudinal relationship between perceived stress and C-reactive protein (CRP) is limited. We explored the relationship between perceived stress and CRP concurrently and across 2 and 4years in 383 men and women. Multiple linear regressions examined the cross-sectional and longitudinal relationships between baseline stress and counter-stress scores with CRP at baseline, 2years after baseline and 4years after baseline, while controlling for covariates (age, smoking status, anti-inflammatory use, oral contraceptive use, physical activity, menopausal status, years since onset of menopause, post-menopausal hormone use and body mass index). Results indicate that stress and counter-stress were not related to CRP in either men or women at study baseline or 2years later. Across a 4-year time frame, higher stress values were related to higher CRP values in women, but not men. Counter-stress was not related to CRP values in men or women across the 4years. This study highlights the importance of examining the cross-sectional and longitudinal relationship between perceived stress and inflammation separately in men and women. Copyright © 2013 John Wiley & Sons, Ltd. © 2013 John Wiley & Sons, Ltd.
U2 - https://doi.org/10.1002/smi.2507
DO - https://doi.org/10.1002/smi.2507
M3 - Article
C2 - 23818431
SN - 1532-3005
VL - 30
SP - 158
EP - 165
JO - STRESS AND HEALTH
JF - STRESS AND HEALTH
IS - 2
ER -