TY - JOUR
T1 - Cutaneous Leishmaniasis (Leishmania major Infection) in Dutch Troops Deployed in Northern Afghanistan: Epidemiology, Clinical Aspects, and Treatment
AU - van Thiel, Pieter-Paul
AU - Leenstra, Tjalling
AU - de Vries, Henry J.
AU - van der Sluis, Allard
AU - van Gool, Tom
AU - Krull, Alex C.
AU - van Vugt, Michèle
AU - de Vries, Peter J.
AU - Zeegelaar, Jimmy E.
AU - Bart, Aldert
AU - van der Meide, Wendy F.
AU - Schallig, Henk D. F. H.
AU - Faber, William R.
AU - Kager, Piet A.
PY - 2010
Y1 - 2010
N2 - Cutaneous leishmaniasis caused by Leishmania major infection affected 172 (18.3%) of 938 Dutch military troops deployed in northern Afghanistan in 2005. The high attack rate was a result of initial insufficient availability of means of prevention and insufficient adherence to preventive measures. At presentation, the lymphatic system was involved in 24.8%. Treatment with intralesional injections of antimony with or without cryotherapy was satisfactory, but 19.5% of patients received secondary treatment with miltefosine. Six months after treatment, 128 (77.1%) of 166 treated patients were cured, 16 (9.6%) were lost to follow-up, and 22 (13.3%) already experienced cure at six weeks but were not seen at six months. Natural evolution played a role in this observational study, which showed cure of all patients seen at six months. In general, management of cutaneous leishmaniasis was feasible under field conditions
AB - Cutaneous leishmaniasis caused by Leishmania major infection affected 172 (18.3%) of 938 Dutch military troops deployed in northern Afghanistan in 2005. The high attack rate was a result of initial insufficient availability of means of prevention and insufficient adherence to preventive measures. At presentation, the lymphatic system was involved in 24.8%. Treatment with intralesional injections of antimony with or without cryotherapy was satisfactory, but 19.5% of patients received secondary treatment with miltefosine. Six months after treatment, 128 (77.1%) of 166 treated patients were cured, 16 (9.6%) were lost to follow-up, and 22 (13.3%) already experienced cure at six weeks but were not seen at six months. Natural evolution played a role in this observational study, which showed cure of all patients seen at six months. In general, management of cutaneous leishmaniasis was feasible under field conditions
U2 - https://doi.org/10.4269/ajtmh.2010.10-0143
DO - https://doi.org/10.4269/ajtmh.2010.10-0143
M3 - Article
C2 - 21118937
SN - 0002-9637
VL - 83
SP - 1295
EP - 1300
JO - American journal of tropical medicine and hygiene
JF - American journal of tropical medicine and hygiene
IS - 6
ER -