Cystic echinococcosis in sub-Saharan Africa

Kerstin Wahlers, Colin N. Menezes, Michelle L. Wong, Eberhard Zeyhle, Mohammed E. Ahmed, Michael Ocaido, Cornelis Stijnis, Thomas Romig, Peter Kern, Martin P. Grobusch

Research output: Contribution to journalReview articleAcademicpeer-review

73 Citations (Scopus)

Abstract

Cystic echinococcosis is regarded as endemic in sub-Saharan Africa; however, for most countries only scarce data, if any, exist. For most of the continent, information about burden of disease is not available; neither are data for the animal hosts involved in the lifecycle of the parasite, thus making introduction of preventive measures difficult. Available evidence suggests that several species or strains within the Echinococcus granulosus complex are prevalent in sub-Saharan Africa and that these strains might be associated with varying virulence and host preference. Treatment strategies (chemotherapy, percutaneous radiological techniques, but mainly surgery) predominantly target active disease. Prevention strategies encompass anthelmintic treatment of dogs, slaughter hygiene, surveillance, and health-educational measures. Existing data are suggestive of unusual clinical presentations of cystic echinococcosis in some parts of the continent, for which the causes are speculative
Original languageEnglish
Pages (from-to)871-880
JournalLancet infectious diseases
Volume12
Issue number11
DOIs
Publication statusPublished - 2012

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