TY - JOUR
T1 - Cytogenetic changes in fish exposed to water of the river Rhine
AU - PREIN, A. E.
AU - THIE, G. M.
AU - Alink, G. M.
AU - Koeman, J. H.
AU - Poels, C. L.
PY - 1978
Y1 - 1978
N2 - The induction of chromosome aberrations in fishes, exposed to Rhinewater, was investigated. The mudminnow, Umbra pygmaea, was chosen for this study, because of its ideal karyotype of 22 large chromosomes. Gill cells were used for chromosome studies. Fish, kept in Rhinewater for 11 days had chromosome breaks in approximately 30% of the metaphases studied. Control fish, exposed to a very good quality of untreated groundwater had breaks in about 8% of the metaphases. Several Rhinewater extracts were tested for their mutagenic potential in the Salmonella-microsome test. The fraction of aromatic compounds was found to be positive. This may indicate that one or more of the compounds present in this fraction were also responsible for the cytogenetic changes found in the fish
AB - The induction of chromosome aberrations in fishes, exposed to Rhinewater, was investigated. The mudminnow, Umbra pygmaea, was chosen for this study, because of its ideal karyotype of 22 large chromosomes. Gill cells were used for chromosome studies. Fish, kept in Rhinewater for 11 days had chromosome breaks in approximately 30% of the metaphases studied. Control fish, exposed to a very good quality of untreated groundwater had breaks in about 8% of the metaphases. Several Rhinewater extracts were tested for their mutagenic potential in the Salmonella-microsome test. The fraction of aromatic compounds was found to be positive. This may indicate that one or more of the compounds present in this fraction were also responsible for the cytogenetic changes found in the fish
U2 - https://doi.org/10.1016/0048-9697(78)90019-0
DO - https://doi.org/10.1016/0048-9697(78)90019-0
M3 - Article
C2 - 663605
SN - 0048-9697
VL - 9
SP - 287
EP - 291
JO - Science of the total environment
JF - Science of the total environment
IS - 3
ER -