Abstract
Three cell lines derived from two metastases of a mammary carcinoma in a femal dog were analyzed cytogenetically. All three cell lines showed a modal chromosome number of 76, with ranges of 74-77, 72-78, and 73-78. A biarmed chromosome in addition to the X chromosomes was observed in all cells of one cell line, and in a part of the cells of the other two cell lines. Results of banding analyses indicated that this chromosome was identical in the three cell lines, and can thus be considered a clonal marker. Additional biarmed chromosomes have not been reported previously from mammary tumor cells, although their presence is rather common in other canine neoplasms.
| Original language | English |
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| Pages (from-to) | 1241-1244 |
| Number of pages | 4 |
| Journal | Anticancer research |
| Volume | 9 |
| Issue number | 4 |
| Publication status | Published - 1989 |