De behandeling van ductaal carcinoma in situ (DCIS) van de mamma

A. H. Westenberg, E. J. T. Rutgers, J. L. Peterse, J. H. C. L. Hendriks, L. V. A. M. Beex, G. van Tienhoven

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Ductal carcinoma in situ (DCIS) of the breast is diagnosed more and more often in the Netherlands as a result of mammographic population screening and improved mammography techniques. Mastectomy and local excision, with or without radiotherapy, are used for the treatment of DCIS, but breast-conserving therapy seems a logical option in view of the favourable prognosis. Radiotherapy following total excision of DCIS reduces the local recurrence rate by half. Incomplete excision of DCIS is associated with a higher rate of local recurrence, which is invasive in about 50% of the cases and can therefore affect the prognosis adversely. There are conflicting opinions in the literature as to which patients with DCIS can be treated with breast-conserving therapy and whether local excision should be followed by radiotherapy, as is the case for breast-conserving treatment of invasive mammary carcinoma. The diagnosis and treatment of DCIS are therefore complex and require a multidisciplinary approach. Patients may be selected for breast-conserving therapy on the basis of diagnostic characteristics and risk factors.
Original languageDutch
Pages (from-to)2157-2161
JournalNederlands Tijdschrift voor Geneeskunde
Issue number44
Publication statusPublished - 2003

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