TY - JOUR
T1 - De ziekte van von Willebrand in Nederland: de WiN-studie
AU - Sanders, Yvonne V.
AU - de Wee, Eva M.
AU - Meijer, Karina
AU - Eikenboom, J.
AU - van der Bom, Jeroen G.
AU - Fijnvandraat, C. J. Karin
AU - Laros-van Gorkom, Britta A. P.
AU - Cnossen, Marjon H.
AU - Mauser-Bunschoten, Evelien P.
AU - Leebeek, Frank W. G.
PY - 2014
Y1 - 2014
N2 - Von Willebrand disease is the most common inherited bleeding disorder and is characterised by mucocutaneous bleeding. Von Willebrand disease is caused by reduced levels or reduced function of von Willebrand factor. Depending on the cause, von Willebrand disease is distinguished into various types with their own characteristics and treatment options. The frequency and severity of bleeding in patients with von Willebrand disease is strongly determined by von Willebrand factor levels, factor VIII levels and the type of von Willebrand disease. Eighty-five percent of all adult females with von Willebrand disease reports menorrhagia. A high percentage have postpartum excessive blood loss (37% of all deliveries). The quality of life is reduced in patients with von Willebrand disease. Patients with von Willebrand disease have a reduced risk of arterial thrombosis such as a myocardial or cerebral infarction
AB - Von Willebrand disease is the most common inherited bleeding disorder and is characterised by mucocutaneous bleeding. Von Willebrand disease is caused by reduced levels or reduced function of von Willebrand factor. Depending on the cause, von Willebrand disease is distinguished into various types with their own characteristics and treatment options. The frequency and severity of bleeding in patients with von Willebrand disease is strongly determined by von Willebrand factor levels, factor VIII levels and the type of von Willebrand disease. Eighty-five percent of all adult females with von Willebrand disease reports menorrhagia. A high percentage have postpartum excessive blood loss (37% of all deliveries). The quality of life is reduced in patients with von Willebrand disease. Patients with von Willebrand disease have a reduced risk of arterial thrombosis such as a myocardial or cerebral infarction
M3 - Article
C2 - 24800796
SN - 0028-2162
VL - 158
SP - A6518
JO - Nederlands Tijdschrift voor Geneeskunde
JF - Nederlands Tijdschrift voor Geneeskunde
ER -