TY - JOUR
T1 - Decreased Appetite is Associated with Sarcopenia-Related Outcomes in Acute Hospitalized Older Adults
AU - Hospital-ADL study group
AU - van Dronkelaar, C.
AU - Tieland, M.
AU - Aarden, J.J.
AU - Reichardt, L.A.
AU - van Seben, R.
AU - van der Schaaf, M.
AU - van der Esch, M.
AU - Engelbert, R.H.H.
AU - Twisk, J.W.R.
AU - Bosch, J.A.
AU - Buurman, B.M.
N1 - In Special Issue ''Older Individuals' Nutrition''
PY - 2019/4/25
Y1 - 2019/4/25
N2 - Decreased appetite is one of the main risk factors of malnutrition. Little is known on how appetite changes during hospitalization and after discharge and how it relates with sarcopenia-related outcomes. We analyzed data of the Hospital-ADL study, a multicenter prospective cohort study that followed 400 acutely hospitalized older adults (≥70 year). Appetite (SNAQ), handgrip strength (Jamar), muscle mass (BIA), mobility (DEMMI), and physical performance (SPPB) were assessed within 48 h of admission, at discharge, and at one and three months post-discharge. The course of decreased appetite was analysed by Generalised Estimating Equations. Linear Mixed Model was used to analyse the associations between decreased appetite and the sarcopenia-related outcomes. Decreased appetite was reported by 51% at hospital admission, 34% at discharge, 28% one month post-discharge, and 17% three months post-discharge. Overall, decreased appetite was associated with lower muscle strength (β = −1.089, p = 0.001), lower mobility skills (β = −3.893, p < 0.001), and lower physical performance (β = −0.706, p < 0.001) but not with muscle mass (β = −0.023, p = 0.920). In conclusion, decreased appetite was highly prevalent among acute hospitalized older adults and remained prevalent, although less, after discharge. Decreased appetite was significantly associated with negative sarcopenia-related outcomes, which underlines the need for assessment and monitoring of decreased appetite during and post hospitalization.
AB - Decreased appetite is one of the main risk factors of malnutrition. Little is known on how appetite changes during hospitalization and after discharge and how it relates with sarcopenia-related outcomes. We analyzed data of the Hospital-ADL study, a multicenter prospective cohort study that followed 400 acutely hospitalized older adults (≥70 year). Appetite (SNAQ), handgrip strength (Jamar), muscle mass (BIA), mobility (DEMMI), and physical performance (SPPB) were assessed within 48 h of admission, at discharge, and at one and three months post-discharge. The course of decreased appetite was analysed by Generalised Estimating Equations. Linear Mixed Model was used to analyse the associations between decreased appetite and the sarcopenia-related outcomes. Decreased appetite was reported by 51% at hospital admission, 34% at discharge, 28% one month post-discharge, and 17% three months post-discharge. Overall, decreased appetite was associated with lower muscle strength (β = −1.089, p = 0.001), lower mobility skills (β = −3.893, p < 0.001), and lower physical performance (β = −0.706, p < 0.001) but not with muscle mass (β = −0.023, p = 0.920). In conclusion, decreased appetite was highly prevalent among acute hospitalized older adults and remained prevalent, although less, after discharge. Decreased appetite was significantly associated with negative sarcopenia-related outcomes, which underlines the need for assessment and monitoring of decreased appetite during and post hospitalization.
KW - Malnutrition
KW - Mobility
KW - Muscle mass
KW - Muscle strength
KW - Nutrition
KW - Physical performance
KW - Post-acute care
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85065322287&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/31027202
UR - http://www.scopus.com/inward/record.url?scp=85065322287&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85065322287&partnerID=8YFLogxK
U2 - https://doi.org/10.3390/nu11040932
DO - https://doi.org/10.3390/nu11040932
M3 - Article
C2 - 31027202
SN - 2072-6643
VL - 11
SP - 1
EP - 12
JO - NUTRIENTS
JF - NUTRIENTS
IS - 4
M1 - 932
ER -