TY - JOUR
T1 - Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group
T2 - update by the ASAS MRI working group
AU - Lambert, Robert G. W.
AU - Bakker, Pauline A. C.
AU - van der Heijde, Désirée
AU - Weber, Ulrich
AU - Rudwaleit, Martin
AU - Hermann, K. G.
AU - Sieper, Joachim
AU - Baraliakos, Xenofon
AU - Bennett, Alex
AU - Braun, Jürgen
AU - Burgos-Vargas, Rubén
AU - Dougados, Maxime
AU - Pedersen, Susanne Juhl
AU - Jurik, Anne Grethe
AU - Maksymowych, Walter P.
AU - Marzo-Ortega, Helena
AU - Østergaard, Mikkel
AU - Poddubnyy, Denis
AU - Reijnierse, Monique
AU - van den Bosch, Filip
AU - van der Horst-Bruinsma, Irene
AU - Landewé, Robert
PY - 2016/11
Y1 - 2016/11
N2 - To review and update the existing definition of a positive MRI for classification of axial spondyloarthritis (SpA). The Assessment in SpondyloArthritis International Society (ASAS) MRI working group conducted a consensus exercise to review the definition of a positive MRI for inclusion in the ASAS classification criteria of axial SpA. Existing definitions and new data relevant to the MRI diagnosis and classification of sacroiliitis and spondylitis in axial SpA, published since the ASAS definition first appeared in print in 2009, were reviewed and discussed. The precise wording of the existing definition was examined in detail and the data and a draft proposal were presented to and voted on by the ASAS membership. The clear presence of bone marrow oedema on MRI in subchondral bone is still considered to be the defining observation that determines the presence of active sacroiliitis. Structural damage lesions seen on MRI may contribute to a decision by the observer that inflammatory lesions are genuinely due to SpA but are not required to meet the definition. The existing definition was clarified adding guidelines and images to assist in the application of the definition. The definition of a positive MRI for classification of axial SpA should continue to primarily depend on the imaging features of 'active sacroiliitis' until more data are available regarding MRI features of structural damage in the sacroiliac joint and MRI features in the spine and their utility when used for classification purposes
AB - To review and update the existing definition of a positive MRI for classification of axial spondyloarthritis (SpA). The Assessment in SpondyloArthritis International Society (ASAS) MRI working group conducted a consensus exercise to review the definition of a positive MRI for inclusion in the ASAS classification criteria of axial SpA. Existing definitions and new data relevant to the MRI diagnosis and classification of sacroiliitis and spondylitis in axial SpA, published since the ASAS definition first appeared in print in 2009, were reviewed and discussed. The precise wording of the existing definition was examined in detail and the data and a draft proposal were presented to and voted on by the ASAS membership. The clear presence of bone marrow oedema on MRI in subchondral bone is still considered to be the defining observation that determines the presence of active sacroiliitis. Structural damage lesions seen on MRI may contribute to a decision by the observer that inflammatory lesions are genuinely due to SpA but are not required to meet the definition. The existing definition was clarified adding guidelines and images to assist in the application of the definition. The definition of a positive MRI for classification of axial SpA should continue to primarily depend on the imaging features of 'active sacroiliitis' until more data are available regarding MRI features of structural damage in the sacroiliac joint and MRI features in the spine and their utility when used for classification purposes
U2 - https://doi.org/10.1136/annrheumdis-2015-208642
DO - https://doi.org/10.1136/annrheumdis-2015-208642
M3 - Article
C2 - 26768408
SN - 0003-4967
VL - 75
SP - 1958
EP - 1963
JO - Annals of the rheumatic diseases
JF - Annals of the rheumatic diseases
IS - 11
ER -