TY - JOUR
T1 - Delay in the diagnosis and treatment of tuberculosis in prisons in Mato Grosso do Sul, Brazil
AU - Ribeiro, Carla Celina
AU - Santos, Andrea da Silva
AU - Tshua, Daniel Henrique
AU - de Oliveira, Roberto Dias
AU - Lemos, Everton Ferreira
AU - Bourdillon, Paul
AU - Laranjeira, Alexandre
AU - Gonçalves, Crhistinne Cavalheiro Maymone
AU - Andrews, Jason
AU - Ko, Albert
AU - Croda, Julio
N1 - Funding Information: We thank the State Agency of Administration Prisons (AGEPEN) for their full support during the study period, the study participants for their kind cooperation during the data collection process, and the Central Laboratory (LACEN) of the state of Mato Grosso do Sul for the support in the accomplishment of the laboratory tests. Publisher Copyright: © 2023, Sociedade Brasileira de Medicina Tropical. All rights reserved.
PY - 2023
Y1 - 2023
N2 - Background: The number of tuberculosis (TB) cases in prisons is higher than that in the general population and has been reported as the most common cause of death in prisons. This study evaluated the delay in the diagnosis and treatment of TB in Brazilian prisons. Methods: A retrospective cohort study was conducted between 2007 and 2015 using data from the five largest male prisons in Mato Grosso do Sul, Brazil. TB case data was collected from the National Database of Notifiable Diseases (SINAN), GAL-LACEN, and prison medical records. The following variables were recorded: prison, year of diagnosis, age, race, education, HIV status, smoking status, comorbidities, number of symptoms, percentage of cures, delay in diagnosis, patient delay, provider delay, laboratory delay, and delay in treatment. Descriptive statistics were used for the variables of interest. Results: A total of 362 pulmonary TB cases were identified. The average time between the first symptom and reporting of data was 9days. The mean time between symptom onset and laboratory diagnosis was 91 days. The average time from symptom onset to firsconsultation was 80 days. The time between diagnosis and treatment initiation was 5 days. Conclusions: Delays were significant between reporting of the first symptoms and diagnosis and significantly smaller from the timbetween notification and start of treatment. Control strategies should be implemented to diagnose cases through active screening, tavoid delays in diagnosis and treatment, and to reduce TB transmission.
AB - Background: The number of tuberculosis (TB) cases in prisons is higher than that in the general population and has been reported as the most common cause of death in prisons. This study evaluated the delay in the diagnosis and treatment of TB in Brazilian prisons. Methods: A retrospective cohort study was conducted between 2007 and 2015 using data from the five largest male prisons in Mato Grosso do Sul, Brazil. TB case data was collected from the National Database of Notifiable Diseases (SINAN), GAL-LACEN, and prison medical records. The following variables were recorded: prison, year of diagnosis, age, race, education, HIV status, smoking status, comorbidities, number of symptoms, percentage of cures, delay in diagnosis, patient delay, provider delay, laboratory delay, and delay in treatment. Descriptive statistics were used for the variables of interest. Results: A total of 362 pulmonary TB cases were identified. The average time between the first symptom and reporting of data was 9days. The mean time between symptom onset and laboratory diagnosis was 91 days. The average time from symptom onset to firsconsultation was 80 days. The time between diagnosis and treatment initiation was 5 days. Conclusions: Delays were significant between reporting of the first symptoms and diagnosis and significantly smaller from the timbetween notification and start of treatment. Control strategies should be implemented to diagnose cases through active screening, tavoid delays in diagnosis and treatment, and to reduce TB transmission.
KW - Brazil
KW - Delayed diagnosis
KW - Prisons
KW - Time to treatment
KW - Tuberculosis
UR - http://www.scopus.com/inward/record.url?scp=85165646513&partnerID=8YFLogxK
U2 - https://doi.org/10.1590/0037-8682-0015-2023
DO - https://doi.org/10.1590/0037-8682-0015-2023
M3 - Article
C2 - 37493729
SN - 0037-8682
VL - 56
JO - Revista da Sociedade Brasileira de Medicina Tropical
JF - Revista da Sociedade Brasileira de Medicina Tropical
M1 - e0015-2023
ER -