Determinants of the therapeutic efficacy of thymidylate synthase inhibitors

G J Peters, C M Kuiper, B van Triest, H Backus, C L van der Wilt, J A van Laar, G Jansen, C J van Groeningen, H M Pinedo

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)699-704
Number of pages6
JournalAdvances in experimental medicine and biology
Publication statusPublished - 1998


  • Animals
  • Antimetabolites, Antineoplastic/pharmacology
  • Apoptosis/drug effects
  • Drug Resistance, Neoplasm
  • Enzyme Inhibitors/pharmacology
  • Fluorouracil/pharmacology
  • Humans
  • Thymidylate Synthase/antagonists & inhibitors
  • Treatment Outcome
  • Tumor Cells, Cultured

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