TY - JOUR
T1 - Developments in radiation techniques for thoracic malignancies
AU - Finazzi, Tobias
AU - Schneiders, Famke L.
AU - Senan, Suresh
N1 - Funding Information: Conflict of interest: T. Finazzi reports personal fees from AstraZeneca, outside the submitted work. F.L. Schneiders has nothing to disclose. S. Senan reports grants and personal fees from AstraZeneca and Varian Medical Systems, grants from ViewRay Inc., and personal fees from MSD and Celgene, outside the submitted work. Publisher Copyright: © The authors 2021. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/6/30
Y1 - 2021/6/30
N2 - Radiation therapy is a cornerstone of modern lung cancer treatment alongside surgery, chemotherapy, immunotherapy and targeted therapies. Advances in radiotherapy techniques have enhanced the accuracy of radiation delivery, which has contributed to the evolution of radiation therapy into a guideline-recommended treatment in both early-stage and locally advanced nonsmall cell lung cancer. Furthermore, although radiotherapy has long been used for palliation of disease in advanced lung cancer, it is increasingly having a role as a locally ablative treatment in patients with oligometastatic disease.This review provides an overview of recent developments in radiation techniques, particularly for non-radiation oncologists who are involved in the care of lung cancer patients. Technical advances are discussed, and findings of recent clinical trials are highlighted, all of which have led to a changing perception of the role of radiation therapy in multidisciplinary care.
AB - Radiation therapy is a cornerstone of modern lung cancer treatment alongside surgery, chemotherapy, immunotherapy and targeted therapies. Advances in radiotherapy techniques have enhanced the accuracy of radiation delivery, which has contributed to the evolution of radiation therapy into a guideline-recommended treatment in both early-stage and locally advanced nonsmall cell lung cancer. Furthermore, although radiotherapy has long been used for palliation of disease in advanced lung cancer, it is increasingly having a role as a locally ablative treatment in patients with oligometastatic disease.This review provides an overview of recent developments in radiation techniques, particularly for non-radiation oncologists who are involved in the care of lung cancer patients. Technical advances are discussed, and findings of recent clinical trials are highlighted, all of which have led to a changing perception of the role of radiation therapy in multidisciplinary care.
UR - http://www.scopus.com/inward/record.url?scp=85105459336&partnerID=8YFLogxK
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85105459336&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/33952599
U2 - https://doi.org/10.1183/16000617.0224-2020
DO - https://doi.org/10.1183/16000617.0224-2020
M3 - Article
C2 - 33952599
SN - 0905-9180
VL - 30
JO - European Respiratory Review
JF - European Respiratory Review
IS - 160
M1 - 200224
ER -