Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement from the American Heart Association

Gustavo Saposnik, Cheryl Bushnell, Jonathan M. Coutinho, Thalia S. Field, Karen L. Furie, Najibah Galadanci, Wayneho Kam, Fenella C. Kirkham, Norma D. McNair, Aneesh B. Singhal, Vincent Thijs, Victor X. D. Yang

Research output: Contribution to journalReview articleAcademicpeer-review

6 Citations (Scopus)

Abstract

Cerebral venous thrombosis accounts for 0.5% to 3% of all strokes. The most vulnerable populations include young individuals, women of reproductive age, and patients with a prothrombotic state. The clinical presentation of cerebral venous thrombosis is diverse (eg, headaches, seizures), requiring a high level of clinical suspicion. Its diagnosis is based primarily on magnetic resonance imaging/magnetic resonance venography or computed tomography/computed tomographic venography. The clinical course of cerebral venous thrombosis may be difficult to predict. Death or dependence occurs in 10% to 15% of patients despite intensive medical treatment. This scientific statement provides an update of the 2011 American Heart Association scientific statement for the diagnosis and management of cerebral venous thrombosis. Our focus is on advances in the diagnosis and management decisions of patients with suspected cerebral venous thrombosis. We discuss evidence for the use of anticoagulation and endovascular therapies and considerations for craniectomy. We also provide an algorithm to optimize the management of patients with cerebral venous thrombosis and those with progressive neurological deterioration or thrombus propagation despite maximal medical therapy.
Original languageEnglish
Pages (from-to)E77-E90
JournalStroke
Volume55
Issue number3
DOIs
Publication statusPublished - 1 Mar 2024

Keywords

  • AHA Scientific Statements
  • anticoagulants
  • headaches
  • intracranial thrombosis
  • seizure
  • sinus thrombosis
  • venous thrombosis

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