Disturbance of cerebral neuronal migration following congenital parvovirus B19 infection

Lourens Rasmus Pistorius, Jaime Smal, Timo Robert de Haan, Godelieve C. M. L. Page-Christiaens, Malgorzata Verboon-Maciolek, Dick Oepkes, Linda S. de Vries

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Abstract

We describe the clinical course of an infant who presented with severe fetal anemia and fetal hydrops following congenital parvovirus B19 infection before 16 gestational weeks. The fetus was treated by cordocentesis and intrauterine transfusion at 18 weeks. The infant demonstrated mild unilateral ventriculomegaly on antenatal magnetic resonance imaging, and polymicrogyria and heterotopia on postnatal magnetic resonance imaging. This adds to the evidence in recent literature of central nervous system damage associated with congenital parvovirus B19 infection
Original languageEnglish
Pages (from-to)491-494
JournalFetal Diagnosis and Therapy
Volume24
Issue number4
DOIs
Publication statusPublished - 2008

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