Abstract
Controversy exists on whether or not the epidermal keratinizing squamous epithelium of skin grafts and flaps applied to line a neovagina changes histologically to a nonkeratinizing mucosal type squamous epithelium after vaginoplasty in male-to-female transsexuals. To end this discussion, the aim of this study was to objectify the short-term and long-term histologic aspect of this neovaginal epithelial lining. Biopsies were taken from the epithelium lining of the neovagina of 9 male-to-female transsexuals, from the moment of vaginoplasty up to 14 years after. These were stained with hematoxylin-eosin and periodic acid-Schiff stain for histologic comparison to normal vaginal biopsies. Because no changes that might have been induced by local influences or hormonal therapy were found, we concluded that short-term and long-term changes in the histologic aspect of inverted skin flaps do not occur after penile and scrotal skin vaginoplasty in male-to-female transsexuals.
Original language | English |
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Pages (from-to) | 546-9 |
Number of pages | 4 |
Journal | Annals of Plastic Surgery |
Volume | 59 |
Issue number | 5 |
DOIs | |
Publication status | Published - Nov 2007 |
Keywords
- Adult
- Female
- Histology
- Hormones/therapeutic use
- Humans
- Keratosis/therapy
- Male
- Middle Aged
- Mucous Membrane/pathology
- Penis/surgery
- Reconstructive Surgical Procedures/methods
- Scrotum/surgery
- Surgical Flaps
- Transsexualism/surgery
- Vagina/anatomy & histology