TY - JOUR
T1 - Driven progressive evolution of genome sequence complexity in Cyanobacteria
AU - Moya, Andrés
AU - Oliver, José L.
AU - Verdú, Miguel
AU - Delaye, Luis
AU - Arnau, Vicente
AU - Bernaola-Galván, Pedro
AU - de la Fuente, Rebeca
AU - Díaz, Wladimiro
AU - Gómez-Martín, Cristina
AU - González, Francisco M.
AU - Latorre, Amparo
AU - Lebrón, Ricardo
AU - Román-Roldán, Ramón
N1 - Funding Information: This project was funded by grants from the Spanish Minister of Science, Innovation and Universities (former Spanish Minister of Economy and Competitiveness) to A.M. (Project SAF2015-65878-R), J.L.O. (Project AGL2017-88702-C2-2-R) and A.L. (Project PGC2018-099344-B-I00), grant from Generalitat Valenciana to A.M. (Project Prometeo/2018/A/133), and co-financed by the European Regional Development Fund (ERDF). This project was also supported by a Fulbright fellowship (Spanish Minister of Science, Innovation and Universities) to A.M. for a sabbatical leave at Harvard University. The authors thank to Fernando Baquero, Mitchell Distin and Guillermo Ponz for critical reading of the manuscript. Publisher Copyright: © 2020, The Author(s).
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Progressive evolution, or the tendency towards increasing complexity, is a controversial issue in biology, which resolution entails a proper measurement of complexity. Genomes are the best entities to address this challenge, as they encode the historical information of a species’ biotic and environmental interactions. As a case study, we have measured genome sequence complexity in the ancient phylum Cyanobacteria. To arrive at an appropriate measure of genome sequence complexity, we have chosen metrics that do not decipher biological functionality but that show strong phylogenetic signal. Using a ridge regression of those metrics against root-to-tip distance, we detected positive trends towards higher complexity in three of them. Lastly, we applied three standard tests to detect if progressive evolution is passive or driven—the minimum, ancestor–descendant, and sub-clade tests. These results provide evidence for driven progressive evolution at the genome-level in the phylum Cyanobacteria.
AB - Progressive evolution, or the tendency towards increasing complexity, is a controversial issue in biology, which resolution entails a proper measurement of complexity. Genomes are the best entities to address this challenge, as they encode the historical information of a species’ biotic and environmental interactions. As a case study, we have measured genome sequence complexity in the ancient phylum Cyanobacteria. To arrive at an appropriate measure of genome sequence complexity, we have chosen metrics that do not decipher biological functionality but that show strong phylogenetic signal. Using a ridge regression of those metrics against root-to-tip distance, we detected positive trends towards higher complexity in three of them. Lastly, we applied three standard tests to detect if progressive evolution is passive or driven—the minimum, ancestor–descendant, and sub-clade tests. These results provide evidence for driven progressive evolution at the genome-level in the phylum Cyanobacteria.
UR - http://www.scopus.com/inward/record.url?scp=85094958040&partnerID=8YFLogxK
U2 - https://doi.org/10.1038/s41598-020-76014-4
DO - https://doi.org/10.1038/s41598-020-76014-4
M3 - Article
C2 - 33149190
SN - 2045-2322
VL - 10
JO - Scientific reports
JF - Scientific reports
IS - 1
M1 - 19073
ER -