Ecological replacement of Enterococcus faecalis by multiresistant clonal complex 17 Enterococcus faecium

J. Top; R. Willems; H. Blok; M. de Regt; K. Jalink; A. Troelstra; B. Goorhuis; M. Bonten

doi:https://doi.org/10.1111/j.1469-0691.2006.01631.x

Ecological replacement of Enterococcus faecalis by multiresistant clonal complex 17 Enterococcus faecium

J. Top, R. Willems, H. Blok, M. de Regt, K. Jalink, A. Troelstra, B. Goorhuis, M. Bonten

Infectious diseases (AMC)

Research output: Contribution to journal › Article › Academic › peer-review

97 Citations (Scopus)

Abstract

The proportion of enterococcal infections caused by ampicillin-resistant Enterococcus faecium (AREfm) in a European hospital increased from 2% in 1994 to 32% in 2005, with prevalence rates of AREfm endemicity of up to 35% in at least six hospital wards. Diabetes mellitus, three or more admissions in the preceding year, and use of beta-lactams and fluoroquinolones, were all associated with AREfm colonisation. Of 217 AREfm isolates that were genotyped, 97% belonged to clonal complex 17 (CC17). This ecological change mimics events preceding the emergence of vancomycin-resistant E. faecium (VREF) in the USA and may presage the emergence of CC17 VREF in European hospitals

Original language	English
Pages (from-to)	316-319
Journal	Clinical Microbiology and Infection
Volume	13
Issue number	3
DOIs	https://doi.org/10.1111/j.1469-0691.2006.01631.x
Publication status	Published - 2007

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https://doi.org/10.1111/j.1469-0691.2006.01631.x

Cite this

@article{21575612092843df804240ae173dcb90,

title = "Ecological replacement of Enterococcus faecalis by multiresistant clonal complex 17 Enterococcus faecium",

abstract = "The proportion of enterococcal infections caused by ampicillin-resistant Enterococcus faecium (AREfm) in a European hospital increased from 2% in 1994 to 32% in 2005, with prevalence rates of AREfm endemicity of up to 35% in at least six hospital wards. Diabetes mellitus, three or more admissions in the preceding year, and use of beta-lactams and fluoroquinolones, were all associated with AREfm colonisation. Of 217 AREfm isolates that were genotyped, 97% belonged to clonal complex 17 (CC17). This ecological change mimics events preceding the emergence of vancomycin-resistant E. faecium (VREF) in the USA and may presage the emergence of CC17 VREF in European hospitals",

author = "J. Top and R. Willems and H. Blok and {de Regt}, M. and K. Jalink and A. Troelstra and B. Goorhuis and M. Bonten",

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T1 - Ecological replacement of Enterococcus faecalis by multiresistant clonal complex 17 Enterococcus faecium

AU - Top, J.

AU - Willems, R.

AU - Blok, H.

AU - de Regt, M.

AU - Jalink, K.

AU - Troelstra, A.

AU - Goorhuis, B.

AU - Bonten, M.

PY - 2007

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N2 - The proportion of enterococcal infections caused by ampicillin-resistant Enterococcus faecium (AREfm) in a European hospital increased from 2% in 1994 to 32% in 2005, with prevalence rates of AREfm endemicity of up to 35% in at least six hospital wards. Diabetes mellitus, three or more admissions in the preceding year, and use of beta-lactams and fluoroquinolones, were all associated with AREfm colonisation. Of 217 AREfm isolates that were genotyped, 97% belonged to clonal complex 17 (CC17). This ecological change mimics events preceding the emergence of vancomycin-resistant E. faecium (VREF) in the USA and may presage the emergence of CC17 VREF in European hospitals

AB - The proportion of enterococcal infections caused by ampicillin-resistant Enterococcus faecium (AREfm) in a European hospital increased from 2% in 1994 to 32% in 2005, with prevalence rates of AREfm endemicity of up to 35% in at least six hospital wards. Diabetes mellitus, three or more admissions in the preceding year, and use of beta-lactams and fluoroquinolones, were all associated with AREfm colonisation. Of 217 AREfm isolates that were genotyped, 97% belonged to clonal complex 17 (CC17). This ecological change mimics events preceding the emergence of vancomycin-resistant E. faecium (VREF) in the USA and may presage the emergence of CC17 VREF in European hospitals

U2 - https://doi.org/10.1111/j.1469-0691.2006.01631.x

DO - https://doi.org/10.1111/j.1469-0691.2006.01631.x

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