TY - JOUR
T1 - EEG synchronisation during sleep-related epileptic seizures as a new tool to discriminate confusional arousals from paroxysmal arousals
T2 - Preliminary findings
AU - Zucconi, Marco
AU - Manconi, M.
AU - Bizzozero, D.
AU - Rundo, F.
AU - Stam, C. J.
AU - Ferini-Strambi, L.
AU - Ferri, R.
PY - 2005/12/1
Y1 - 2005/12/1
N2 - Confusional arousals, paroxysmal arousals (as part of the nocturnal frontal lobe epilepsy) and normal arousals and awakenings from NREM sleep are frequently a challenge for differential diagnosis. In this article we describe the course of synchronisation between different EEG channels during nocturnal seizures in 3 patients with sleep-related epileptic seizures and in 1 patient with sleep terrors. The functional interactions between the different EEG channels during the nocturnal seizures were analysed by means of the so-called synchronisation likelihood (SL). SL is a measure of the dynamical (linear and nonlinear) interdependencies between a time series (EEG channel) and one or more other time series. The main results of our study are the confirmation of a significant increase in EEG synchronisation during sleep-related seizures and the indication that clinically similar ictal motor patterns might be generated by different neurophysiological mechanisms, characterised by different patterns of synchronisation involving multiple or single frequency bands. This new approach might be useful to differentiate motor seizures, emerging from NREM sleep, from parasomnias (arousal disorders) when both ictal and interictal EEGs are uninformative.
AB - Confusional arousals, paroxysmal arousals (as part of the nocturnal frontal lobe epilepsy) and normal arousals and awakenings from NREM sleep are frequently a challenge for differential diagnosis. In this article we describe the course of synchronisation between different EEG channels during nocturnal seizures in 3 patients with sleep-related epileptic seizures and in 1 patient with sleep terrors. The functional interactions between the different EEG channels during the nocturnal seizures were analysed by means of the so-called synchronisation likelihood (SL). SL is a measure of the dynamical (linear and nonlinear) interdependencies between a time series (EEG channel) and one or more other time series. The main results of our study are the confirmation of a significant increase in EEG synchronisation during sleep-related seizures and the indication that clinically similar ictal motor patterns might be generated by different neurophysiological mechanisms, characterised by different patterns of synchronisation involving multiple or single frequency bands. This new approach might be useful to differentiate motor seizures, emerging from NREM sleep, from parasomnias (arousal disorders) when both ictal and interictal EEGs are uninformative.
KW - Confusional arousals
KW - Nocturnal frontal lobe epilepsy
KW - Paroxysmal arousals
KW - Seizure neurophysiology
KW - Synchronisation likelihood
UR - http://www.scopus.com/inward/record.url?scp=33645728533&partnerID=8YFLogxK
U2 - https://doi.org/10.1007/s10072-005-0487-5
DO - https://doi.org/10.1007/s10072-005-0487-5
M3 - Article
C2 - 16331396
SN - 1590-1874
VL - 26
JO - Neurological sciences
JF - Neurological sciences
IS - SUPPL. 3
ER -