Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study. Results from the anti-oxidant therapy in chronic renal insufficiency (ATIC) study

P.W. Nanayakkara, C. van Guldener, P.M. ter Wee, P.G. Scheffer, F.J. van Ittersum, J.W.R. Twisk, T. Teerlink, W. van Dorp, C.D.A. Stehouwer

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Background: Patients with chronic kidney disease have an increased risk of cardiovascular disease. Oxidative stress has been proposed to play a role in the development of cardiovascular disease among these patients. Methods:Weconducted a randomized, double-blind trial in 93 patients (Cockcroft-Gault equation: creatinine clearance, 38±15 [mean±SD] mL/min per 1.73 m
Original languageEnglish
Pages (from-to)1262-1270
Number of pages9
JournalArchives of Internal Medicine
Issue number12
Publication statusPublished - 25 Jun 2007

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