Effect of Vitamin B-12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial

A.W. Enneman; C.M.A. Swart; J.P. van Wijngaarden; S.C. van Dijk; A.C. van der Ham; E.M. Brouwer-Brolsma; N.L. van der Zwaluw; R.A.M. Dhonukshe-Rutten; T.J.M. van der Cammen; L.C.P.G. de Groot; J. van Meurs; P. Lips; A. G. Uitterlinden; M.C. Zillikens; N.M. van Schoor; N. van der Velde; Karin M. A. Swart

doi:https://doi.org/10.1007/s00223-015-9968-6

Effect of Vitamin B-12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial

A.W. Enneman, C.M.A. Swart, J.P. van Wijngaarden, S.C. van Dijk, A.C. van der Ham, E.M. Brouwer-Brolsma, N.L. van der Zwaluw, R.A.M. Dhonukshe-Rutten, T.J.M. van der Cammen, L.C.P.G. de Groot, J. van Meurs, P. Lips, A. G. Uitterlinden, M.C. Zillikens, N.M. van Schoor, N. van der Velde, Karin M. A. Swart

Research output: Contribution to journal › Article › Academic › peer-review

32 Citations (Scopus)

Abstract

High plasma homocysteine (Hcy) levels are associated with increased osteoporotic fracture incidence. However, the mechanism remains unclear. We investigated the effect of Hcy-lowering vitamin B

Original language	English
Pages (from-to)	401-409
Journal	Calcified tissue international
Volume	96
Issue number	5
DOIs	https://doi.org/10.1007/s00223-015-9968-6
Publication status	Published - 2015

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Cite this

Enneman, A. W., Swart, C. M. A., van Wijngaarden, J. P., van Dijk, S. C., van der Ham, A. C., Brouwer-Brolsma, E. M., van der Zwaluw, N. L., Dhonukshe-Rutten, R. A. M., van der Cammen, T. J. M., de Groot, L. C. P. G., van Meurs, J., Lips, P., Uitterlinden, A. G., Zillikens, M. C., van Schoor, N. M., van der Velde, N., & Swart, K. M. A. (2015). Effect of Vitamin B-12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial. Calcified tissue international, 96(5), 401-409. https://doi.org/10.1007/s00223-015-9968-6

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title = "Effect of Vitamin B-12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial",

abstract = "High plasma homocysteine (Hcy) levels are associated with increased osteoporotic fracture incidence. However, the mechanism remains unclear. We investigated the effect of Hcy-lowering vitamin B",

author = "A.W. Enneman and C.M.A. Swart and {van Wijngaarden}, J.P. and {van Dijk}, S.C. and {van der Ham}, A.C. and E.M. Brouwer-Brolsma and {van der Zwaluw}, N.L. and R.A.M. Dhonukshe-Rutten and {van der Cammen}, T.J.M. and {de Groot}, L.C.P.G. and {van Meurs}, J. and P. Lips and Uitterlinden, {A. G.} and M.C. Zillikens and {van Schoor}, N.M. and {van der Velde}, N. and Swart, {Karin M. A.}",

year = "2015",

doi = "https://doi.org/10.1007/s00223-015-9968-6",

language = "English",

volume = "96",

pages = "401--409",

journal = "Calcified tissue international",

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Enneman, AW, Swart, CMA, van Wijngaarden, JP, van Dijk, SC, van der Ham, AC, Brouwer-Brolsma, EM, van der Zwaluw, NL, Dhonukshe-Rutten, RAM, van der Cammen, TJM, de Groot, LCPG, van Meurs, J, Lips, P, Uitterlinden, AG, Zillikens, MC, van Schoor, NM , van der Velde, N & Swart, KMA 2015, 'Effect of Vitamin B-12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial', Calcified tissue international, vol. 96, no. 5, pp. 401-409. https://doi.org/10.1007/s00223-015-9968-6

Effect of Vitamin B-12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial. / Enneman, A.W.; Swart, C.M.A.; van Wijngaarden, J.P. et al.
In: Calcified tissue international, Vol. 96, No. 5, 2015, p. 401-409.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Swart, C.M.A.

AU - van Wijngaarden, J.P.

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AU - Dhonukshe-Rutten, R.A.M.

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AU - Zillikens, M.C.

AU - van Schoor, N.M.

AU - van der Velde, N.

AU - Swart, Karin M. A.

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Enneman AW, Swart CMA, van Wijngaarden JP, van Dijk SC, van der Ham AC, Brouwer-Brolsma EM et al. Effect of Vitamin B-12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial. Calcified tissue international. 2015;96(5):401-409. doi: https://doi.org/10.1007/s00223-015-9968-6