TY - JOUR
T1 - Effectiveness of exercise therapy in patients with osteoarthritis of the hip or knee
T2 - A systematic review of randomized clinical trials
AU - Van Baar, Margriet E.
AU - Assendelft, Willem J.J.
AU - Dekker, Joost
AU - Oostendorp, Rob A.B.
AU - Bijlsma, Johannes W.J.
PY - 1999/7
Y1 - 1999/7
N2 - Objective. To review the effectiveness of exercise therapy in patients with osteoarthritis (OA) of the hip or knee. Methods. A computerized literature search of Medline, Erabase, and Cinahl was carried out. Randomized clinical trials on exercise therapy for OA of the hip or knee were selected if treatment had been randomly allocated and if pain, self-reported disability, observed disability, or patient's global assessment of effect had been used as outcome measures. The validity of trials was systematically assessed by independent reviewers. Effect sizes and power estimates were calculated. A best evidence synthesis was conducted, weighting the studies with respect to their validity and power. Results. Six of the 11 assessed trials satisfied at least 50% of the validity criteria. Two trials had sufficient power to detect medium-sized effects. Effect sizes indicated small-to-moderate beneficial effects of exercise therapy on pain, small beneficial effects on both disability outcome measures, and moderate-to-great beneficial effects according to patient's global assessment of effect. Conclusion. There is evidence of beneficial effects of exercise therapy in patients with OA of the hip or knee. However, the small number of good studies restricts drawing firm conclusions.
AB - Objective. To review the effectiveness of exercise therapy in patients with osteoarthritis (OA) of the hip or knee. Methods. A computerized literature search of Medline, Erabase, and Cinahl was carried out. Randomized clinical trials on exercise therapy for OA of the hip or knee were selected if treatment had been randomly allocated and if pain, self-reported disability, observed disability, or patient's global assessment of effect had been used as outcome measures. The validity of trials was systematically assessed by independent reviewers. Effect sizes and power estimates were calculated. A best evidence synthesis was conducted, weighting the studies with respect to their validity and power. Results. Six of the 11 assessed trials satisfied at least 50% of the validity criteria. Two trials had sufficient power to detect medium-sized effects. Effect sizes indicated small-to-moderate beneficial effects of exercise therapy on pain, small beneficial effects on both disability outcome measures, and moderate-to-great beneficial effects according to patient's global assessment of effect. Conclusion. There is evidence of beneficial effects of exercise therapy in patients with OA of the hip or knee. However, the small number of good studies restricts drawing firm conclusions.
UR - http://www.scopus.com/inward/record.url?scp=0033496598&partnerID=8YFLogxK
U2 - https://doi.org/10.1002/1529-0131(199907)42:7<1361::AID-ANR9>3.0.CO;2-9
DO - https://doi.org/10.1002/1529-0131(199907)42:7<1361::AID-ANR9>3.0.CO;2-9
M3 - Article
C2 - 10403263
SN - 0004-3591
VL - 42
SP - 1361
EP - 1369
JO - Arthritis and rheumatism
JF - Arthritis and rheumatism
IS - 7
ER -