TY - JOUR
T1 - Effects of Perinatal Exposure to PCBs on Neuropsychological Functions in the Rotterdam Cohort at 9 Years of Age
AU - Vreugdenhil, Hestein J.I.
AU - Emmen, Harry H.
AU - Mulder, Paul G.H.
AU - Weisglas-Kuperus, Nynke
PY - 2004/1/1
Y1 - 2004/1/1
N2 - PCBs are known for their neurotoxic properties, especially on the developing brain. To increase insight into the neurotoxic effects of PCB exposure, the authors studied the effects of perinatal exposure to environmental levels of these compounds on different neuropsychological domains. In 9-year-old children of the Rotterdam PCB-dioxin cohort, higher prenatal PCB levels were associated with longer response times (RTs), more variation in RTs, and lower scores on the Tower of London (TOL; Shallice, 1982). A longer breast-feeding duration was associated with lower TOL scores and with better spatial organizational skills. There was some evidence of negative effects of lactational exposure to PCBs on scores on the TOL.
AB - PCBs are known for their neurotoxic properties, especially on the developing brain. To increase insight into the neurotoxic effects of PCB exposure, the authors studied the effects of perinatal exposure to environmental levels of these compounds on different neuropsychological domains. In 9-year-old children of the Rotterdam PCB-dioxin cohort, higher prenatal PCB levels were associated with longer response times (RTs), more variation in RTs, and lower scores on the Tower of London (TOL; Shallice, 1982). A longer breast-feeding duration was associated with lower TOL scores and with better spatial organizational skills. There was some evidence of negative effects of lactational exposure to PCBs on scores on the TOL.
UR - http://www.scopus.com/inward/record.url?scp=0842324923&partnerID=8YFLogxK
U2 - https://doi.org/10.1037/0894-4105.18.1.185
DO - https://doi.org/10.1037/0894-4105.18.1.185
M3 - Article
C2 - 14744201
SN - 0894-4105
VL - 18
SP - 185
EP - 193
JO - Neuropsychology
JF - Neuropsychology
IS - 1
ER -