TY - JOUR
T1 - Effects of ROI definition and reconstruction method on quantitative outcome and applicability in a response monitoring trial
AU - Krak, N.C.
AU - Boellaard, R.
AU - Hoekstra, O.S.
AU - Twisk, J.W.R.
AU - Hoekstra, C.J.
AU - Lammertsma, A.A.
PY - 2005/3/1
Y1 - 2005/3/1
N2 - Purpose: Quantitative measurement of tracer uptake in a tumour can be influenced by a number of factors, including the method of defining regions of interest (ROIs) and the reconstruction parameters used. The main purpose of this study was to determine the effects of different ROI methods on quantitative outcome, using two reconstruction methods and the standard uptake value (SUV) as a simple quantitative measure of FDG uptake. Methods: Four commonly used methods of ROI definition (manual placement, fixed dimensions, threshold based and maximum pixel value) were used to calculate SUV (SUV
AB - Purpose: Quantitative measurement of tracer uptake in a tumour can be influenced by a number of factors, including the method of defining regions of interest (ROIs) and the reconstruction parameters used. The main purpose of this study was to determine the effects of different ROI methods on quantitative outcome, using two reconstruction methods and the standard uptake value (SUV) as a simple quantitative measure of FDG uptake. Methods: Four commonly used methods of ROI definition (manual placement, fixed dimensions, threshold based and maximum pixel value) were used to calculate SUV (SUV
UR - http://www.scopus.com/inward/record.url?scp=17644421807&partnerID=8YFLogxK
U2 - https://doi.org/10.1007/s00259-004-1566-1
DO - https://doi.org/10.1007/s00259-004-1566-1
M3 - Article
C2 - 15791438
SN - 1619-7070
VL - 32
SP - 294
EP - 301
JO - European journal of nuclear medicine and molecular imaging
JF - European journal of nuclear medicine and molecular imaging
IS - 3
ER -