Electroconvulsive therapy for the treatment of clozapine nonresponders suffering from schizophrenia--an open label study

K. H. Kho; B. A. Blansjaar; S. de Vries; D. Babuskova; A. H. Zwinderman; D. H. Linszen

doi:https://doi.org/10.1007/s00406-004-0517-y

Electroconvulsive therapy for the treatment of clozapine nonresponders suffering from schizophrenia--an open label study

K. H. Kho, B. A. Blansjaar, S. de Vries, D. Babuskova, A. H. Zwinderman, D. H. Linszen

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

OBJECTIVE: This open label study describes the efficacy of electroconvulsive therapy (ECT) as adjunctive treatment in clozapine nonresponders suffering from schizophrenia. METHOD: The results of clozapine and ECT treatment in 11 clozapine nonresponders suffering from schizophrenia are reported in terms of remission and relapse. RESULTS: Eight patients had a remission with this combination treatment. After remission of symptoms five patients had a relapse. Three of the five patients who relapsed had a second successful ECT course and remained well with maintenance ECT and clozapine. No evidence for adverse effects was found. CONCLUSION: Adjunctive ECT can be efficacious in clozapine nonresponders suffering from schizophrenia

Original language	English
Pages (from-to)	372-379
Journal	European archives of psychiatry and clinical neuroscience
Volume	254
Issue number	6
DOIs	https://doi.org/10.1007/s00406-004-0517-y
Publication status	Published - 2004

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https://doi.org/10.1007/s00406-004-0517-y

Cite this

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title = "Electroconvulsive therapy for the treatment of clozapine nonresponders suffering from schizophrenia--an open label study",

abstract = "OBJECTIVE: This open label study describes the efficacy of electroconvulsive therapy (ECT) as adjunctive treatment in clozapine nonresponders suffering from schizophrenia. METHOD: The results of clozapine and ECT treatment in 11 clozapine nonresponders suffering from schizophrenia are reported in terms of remission and relapse. RESULTS: Eight patients had a remission with this combination treatment. After remission of symptoms five patients had a relapse. Three of the five patients who relapsed had a second successful ECT course and remained well with maintenance ECT and clozapine. No evidence for adverse effects was found. CONCLUSION: Adjunctive ECT can be efficacious in clozapine nonresponders suffering from schizophrenia",

author = "Kho, {K. H.} and Blansjaar, {B. A.} and {de Vries}, S. and D. Babuskova and Zwinderman, {A. H.} and Linszen, {D. H.}",

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T1 - Electroconvulsive therapy for the treatment of clozapine nonresponders suffering from schizophrenia--an open label study

AU - Kho, K. H.

AU - Blansjaar, B. A.

AU - de Vries, S.

AU - Babuskova, D.

AU - Zwinderman, A. H.

AU - Linszen, D. H.

PY - 2004

Y1 - 2004

N2 - OBJECTIVE: This open label study describes the efficacy of electroconvulsive therapy (ECT) as adjunctive treatment in clozapine nonresponders suffering from schizophrenia. METHOD: The results of clozapine and ECT treatment in 11 clozapine nonresponders suffering from schizophrenia are reported in terms of remission and relapse. RESULTS: Eight patients had a remission with this combination treatment. After remission of symptoms five patients had a relapse. Three of the five patients who relapsed had a second successful ECT course and remained well with maintenance ECT and clozapine. No evidence for adverse effects was found. CONCLUSION: Adjunctive ECT can be efficacious in clozapine nonresponders suffering from schizophrenia

AB - OBJECTIVE: This open label study describes the efficacy of electroconvulsive therapy (ECT) as adjunctive treatment in clozapine nonresponders suffering from schizophrenia. METHOD: The results of clozapine and ECT treatment in 11 clozapine nonresponders suffering from schizophrenia are reported in terms of remission and relapse. RESULTS: Eight patients had a remission with this combination treatment. After remission of symptoms five patients had a relapse. Three of the five patients who relapsed had a second successful ECT course and remained well with maintenance ECT and clozapine. No evidence for adverse effects was found. CONCLUSION: Adjunctive ECT can be efficacious in clozapine nonresponders suffering from schizophrenia

U2 - https://doi.org/10.1007/s00406-004-0517-y

DO - https://doi.org/10.1007/s00406-004-0517-y

M3 - Article

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SN - 0940-1334

VL - 254

SP - 372

EP - 379

JO - European archives of psychiatry and clinical neuroscience

JF - European archives of psychiatry and clinical neuroscience

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