Electrophysiological patterning of the heart

B.J.D. Boukens

Electrophysiological patterning of the heart

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

12 Citations (Scopus)

Abstract

The results in this thesis indicate that there is a direct relation between the spatio-temporal activity pattern of particular cardiac transcription factors and the electrophysiological characteristics of myocardial structures. Insight into the mechanisms that regulate the expression of these factors and their target regulatory sequences in ion channel encoding genes, could lead to the identification of new approaches and candidate markers for improved arrhythmogenic risk stratification.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution
Supervisors/Advisors	Christoffels, Vincent, Supervisor Coronel, Ruben, Co-supervisor
Award date	19 Dec 2012
Print ISBNs	9789461909978
Publication status	Published - 2012

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title = "Electrophysiological patterning of the heart",

abstract = "The results in this thesis indicate that there is a direct relation between the spatio-temporal activity pattern of particular cardiac transcription factors and the electrophysiological characteristics of myocardial structures. Insight into the mechanisms that regulate the expression of these factors and their target regulatory sequences in ion channel encoding genes, could lead to the identification of new approaches and candidate markers for improved arrhythmogenic risk stratification.",

author = "B.J.D. Boukens",

note = "Research conducted at: Universiteit van Amsterdam",

year = "2012",

language = "English",

isbn = "9789461909978",

type = "Phd-Thesis - Research and graduation internal",

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AU - Boukens, B.J.D.

N1 - Research conducted at: Universiteit van Amsterdam

PY - 2012

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N2 - The results in this thesis indicate that there is a direct relation between the spatio-temporal activity pattern of particular cardiac transcription factors and the electrophysiological characteristics of myocardial structures. Insight into the mechanisms that regulate the expression of these factors and their target regulatory sequences in ion channel encoding genes, could lead to the identification of new approaches and candidate markers for improved arrhythmogenic risk stratification.

AB - The results in this thesis indicate that there is a direct relation between the spatio-temporal activity pattern of particular cardiac transcription factors and the electrophysiological characteristics of myocardial structures. Insight into the mechanisms that regulate the expression of these factors and their target regulatory sequences in ion channel encoding genes, could lead to the identification of new approaches and candidate markers for improved arrhythmogenic risk stratification.

M3 - Phd-Thesis - Research and graduation internal

SN - 9789461909978

ER -