TY - JOUR
T1 - Epidemiology and population structure of Staphylococcus aureus in various population groups from a rural and semi urban area in Gabon, Central Africa
AU - Ateba Ngoa, Ulysse
AU - Schaumburg, Frieder
AU - Adegnika, Ayola Akim
AU - Kösters, Katrin
AU - Möller, Tina
AU - Fernandes, Jose Francisco
AU - Alabi, Abraham
AU - Issifou, Saadou
AU - Becker, Karsten
AU - Grobusch, Martin Peter
AU - Kremsner, Peter Gottfried
AU - Lell, Bertrand
PY - 2012
Y1 - 2012
N2 - Little data is available on the epidemiology of Staphylococcus aureus in Africa. In the present study we aim at characterizing the population structure of S. aureus in healthy subjects from a rural and a semi-urban area in Lambarene, Gabon as well as in hospital staff and inpatients. In total, 500 subjects were screened for S. aureus colonization of the nares, axillae and inguinal region. Overall, 146 (29%) were positive. We found 46 different spa types. The most frequent spa types were t084 (35%) and the agr II was the most prevalent subtype of the accessory gene regulator (56%, n = 82). Five isolates (3%) were methicillin resistant S. aureus (MRSA). Carriage rates of S. aureus in Gabon are comparable to developed countries. MRSA is for the first time described and could pose a significant health threat in this region with limited access to microbiological laboratory facilities and to adequate antimicrobial agents. (c) 2012 Elsevier B.V. All rights reserved
AB - Little data is available on the epidemiology of Staphylococcus aureus in Africa. In the present study we aim at characterizing the population structure of S. aureus in healthy subjects from a rural and a semi-urban area in Lambarene, Gabon as well as in hospital staff and inpatients. In total, 500 subjects were screened for S. aureus colonization of the nares, axillae and inguinal region. Overall, 146 (29%) were positive. We found 46 different spa types. The most frequent spa types were t084 (35%) and the agr II was the most prevalent subtype of the accessory gene regulator (56%, n = 82). Five isolates (3%) were methicillin resistant S. aureus (MRSA). Carriage rates of S. aureus in Gabon are comparable to developed countries. MRSA is for the first time described and could pose a significant health threat in this region with limited access to microbiological laboratory facilities and to adequate antimicrobial agents. (c) 2012 Elsevier B.V. All rights reserved
U2 - https://doi.org/10.1016/j.actatropica.2012.06.005
DO - https://doi.org/10.1016/j.actatropica.2012.06.005
M3 - Article
C2 - 22750045
SN - 0001-706X
VL - 124
SP - 42
EP - 47
JO - Acta tropica
JF - Acta tropica
IS - 1
ER -