TY - JOUR
T1 - Esophagitis and Barrett esophagus after correction of esophageal atresia
AU - Deurloo, J.A.
AU - Ekkelkamp, S.
AU - Taminiau, J.A.
AU - Kneepkens, C.M.F.
AU - ten Kate, F.W.
AU - Bartelsman, J.F.
AU - Legemate, D.A.
AU - Aronson, D.C.
PY - 2005
Y1 - 2005
N2 - Background: Gastroesopliageal reflux is a frequent problem after esophageal atresia (EA) repair. Our aim was to determine the prevalence of esophagitis and Barrett esophagus more than 10 years after repair of EA. Methods: Ninety-two patients treated between 1973 and 1985 were included in this prospective study. A questionnaire was completed by 86 patients; esophagogastroscopy was performed in 49 patients. Results: Only 36 patients had no complaints at all. Thirty-one patients complained of difficulties swallowing solid food; 23 complained of heartburn. Esophagogastroscopy revealed grade 3 esophagitis in 2 patients and a macroscopic image of Barrett esophagus in 2. Histology showed esophagitis in 30 patients, gastric inetaplasia in 3, and no intestinal metaplasia (Barrett esophagus). Conclusions: For epidemiologic reasons, that is, the short interval of follow-up (10 years) and the low compliance of the study group, larger numbers are needed to decide if routine long-term endoscopic screening after repair of EA is necessary. For now, it cannot yet be recommended. The prevalence of symptoms of gastroesophageal reflux disease in this study group is higher than that in the general population, but we found no severe complications of gastroesophageal reflux in the pediatric age group. (c) 2005 Elsevier Inc. All rights reserved
AB - Background: Gastroesopliageal reflux is a frequent problem after esophageal atresia (EA) repair. Our aim was to determine the prevalence of esophagitis and Barrett esophagus more than 10 years after repair of EA. Methods: Ninety-two patients treated between 1973 and 1985 were included in this prospective study. A questionnaire was completed by 86 patients; esophagogastroscopy was performed in 49 patients. Results: Only 36 patients had no complaints at all. Thirty-one patients complained of difficulties swallowing solid food; 23 complained of heartburn. Esophagogastroscopy revealed grade 3 esophagitis in 2 patients and a macroscopic image of Barrett esophagus in 2. Histology showed esophagitis in 30 patients, gastric inetaplasia in 3, and no intestinal metaplasia (Barrett esophagus). Conclusions: For epidemiologic reasons, that is, the short interval of follow-up (10 years) and the low compliance of the study group, larger numbers are needed to decide if routine long-term endoscopic screening after repair of EA is necessary. For now, it cannot yet be recommended. The prevalence of symptoms of gastroesophageal reflux disease in this study group is higher than that in the general population, but we found no severe complications of gastroesophageal reflux in the pediatric age group. (c) 2005 Elsevier Inc. All rights reserved
U2 - https://doi.org/10.1016/j.jpedsurg.2005.05.003
DO - https://doi.org/10.1016/j.jpedsurg.2005.05.003
M3 - Article
C2 - 16080923
SN - 0022-3468
VL - 40
SP - 1227
EP - 1231
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
IS - 8
ER -