TY - JOUR
T1 - Estimating heritability from twin studies
AU - Verweij, Karin J. H.
AU - Mosing, Miriam A.
AU - Zietsch, Brendan P.
AU - Medland, Sarah E.
PY - 2012
Y1 - 2012
N2 - This chapter describes how the heritability of a trait can be estimated using data collected from pairs of twins. The principles of the classical twin design are described, followed by the assumptions and possible extensions of the design. In the second part of this chapter, two example scripts are presented and described, explaining the basic steps for estimating heritability using the statistical program OpenMx. OpenMx and the scripts used for this chapter can be downloaded so that readers can adapt and use the scripts for their own purposes. © 2012 Springer Science+Business Media, LLC.
AB - This chapter describes how the heritability of a trait can be estimated using data collected from pairs of twins. The principles of the classical twin design are described, followed by the assumptions and possible extensions of the design. In the second part of this chapter, two example scripts are presented and described, explaining the basic steps for estimating heritability using the statistical program OpenMx. OpenMx and the scripts used for this chapter can be downloaded so that readers can adapt and use the scripts for their own purposes. © 2012 Springer Science+Business Media, LLC.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84858167593&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/22307698
U2 - https://doi.org/10.1007/978-1-61779-555-8_9
DO - https://doi.org/10.1007/978-1-61779-555-8_9
M3 - Article
C2 - 22307698
SN - 1064-3745
VL - 850
SP - 151
EP - 170
JO - Methods in molecular biology (Clifton, N.J.)
JF - Methods in molecular biology (Clifton, N.J.)
ER -