European Guideline on Achalasia – UEG and ESNM recommendations

R. A. B. Oude Nijhuis, G. Zaninotto, S. Roman, G. E. Boeckxstaens, P. Fockens, M. W. Langendam, A. A. Plumb, A. J. P. M. Smout, E. M. Targarona, A. S. Trukhmanov, B. L. A. M. Weusten, A. J. Bredenoord

Research output: Contribution to journalReview articleAcademicpeer-review

124 Citations (Scopus)

Abstract

Introduction: Achalasia is a primary motor disorder of the oesophagus characterised by absence of peristalsis and insufficient lower oesophageal sphincter relaxation. With new advances and developments in achalasia management, there is an increasing demand for comprehensive evidence-based guidelines to assist clinicians in achalasia patient care. Methods: Guidelines were established by a working group of representatives from United European Gastroenterology, European Society of Neurogastroenterology and Motility, European Society of Gastrointestinal and Abdominal Radiology, and the European Association of Endoscopic Surgery in accordance with the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument. A systematic review of the literature was performed and the certainty of the evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. Recommendations were voted upon using a nominal group technique. Results: These guidelines focus on the definition of achalasia, treatment aims, diagnostic tests, medical, endoscopic and surgical therapy, management of treatment failure, follow-up and oesophageal cancer risk. Conclusion: These multidisciplinary guidelines provide a comprehensive evidence-based framework with recommendations on the diagnosis, treatment and follow-up of adult achalasia patients.
Original languageEnglish
Pages (from-to)13-34
Number of pages22
JournalUnited European gastroenterology journal
Volume8
Issue number1
DOIs
Publication statusPublished - 1 Feb 2020

Keywords

  • Dysphagia
  • manometry
  • motility
  • myotomy
  • oesophagus

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