TY - JOUR
T1 - EUS-B for suspected left adrenal metastasis in lung cancer
AU - Christiansen, Ida Skovgaard
AU - Ahmad, Khaliq
AU - Bodtger, Uffe
AU - Henriette Naur, Therese Maria
AU - Sidhu, Jatinder Singh
AU - Nessar, Rafi
AU - Salih, Goran Nadir
AU - Høegholm, Asbjørn
AU - Annema, Jouke Tabe
AU - Clementsen, Paul Frost
PY - 2020/3/1
Y1 - 2020/3/1
N2 - Background: Several studies have reported the efficacy of esophageal ultrasound-guided fine needle aspiration (EUS-FNA) for the detection of metastases in the left adrenal gland (LAG) in patients with lung cancer. Currently we have only limited evidence based on small studies on the usefulness of EUS-B [endobronchial ultrasound (EBUS) scope into the esophagus] to provide tissue proof of suspected LAG metastases. The objectives of this study are to investigate feasibility, safety and diagnostic yield of EUS-B-FNA in LAG analysis in patients with proven or suspected lung cancer. Methods: In two Danish hospitals, a systematic search in the electronic database for patients who underwent EUS-B-FNA of the LAG for suspected or proven lung cancer was performed retrospectively between January 1st, 2015 and December 31st, 2017. Computed tomography (CT), positron emission tomography-CT, endoscopy, pathology and follow-up data were acquired. Results: One hundred and thirty-five patients were included; the prevalence of biopsy proven LAG malignancy was 30% (40/135). A total of 87% (117/135) of EUS-B-FNA samples were adequate (i.e., containing adrenal or malignant cells). No complications were observed. Conclusions: We present the largest cohort of patients ever reported showing that EUS-B-FNA of the LAG is a safe and feasible procedure and should therefore be used for staging purposes in patients with lung cancer and a suspicious LAG.
AB - Background: Several studies have reported the efficacy of esophageal ultrasound-guided fine needle aspiration (EUS-FNA) for the detection of metastases in the left adrenal gland (LAG) in patients with lung cancer. Currently we have only limited evidence based on small studies on the usefulness of EUS-B [endobronchial ultrasound (EBUS) scope into the esophagus] to provide tissue proof of suspected LAG metastases. The objectives of this study are to investigate feasibility, safety and diagnostic yield of EUS-B-FNA in LAG analysis in patients with proven or suspected lung cancer. Methods: In two Danish hospitals, a systematic search in the electronic database for patients who underwent EUS-B-FNA of the LAG for suspected or proven lung cancer was performed retrospectively between January 1st, 2015 and December 31st, 2017. Computed tomography (CT), positron emission tomography-CT, endoscopy, pathology and follow-up data were acquired. Results: One hundred and thirty-five patients were included; the prevalence of biopsy proven LAG malignancy was 30% (40/135). A total of 87% (117/135) of EUS-B-FNA samples were adequate (i.e., containing adrenal or malignant cells). No complications were observed. Conclusions: We present the largest cohort of patients ever reported showing that EUS-B-FNA of the LAG is a safe and feasible procedure and should therefore be used for staging purposes in patients with lung cancer and a suspicious LAG.
KW - EUS-B
KW - Endobronchial ultrasound (EBUS)
KW - Esophageal ultrasound (EUS)
KW - Left adrenal gland (LAG)
KW - Lung cancer
UR - http://www.scopus.com/inward/record.url?scp=85083090648&partnerID=8YFLogxK
U2 - https://doi.org/10.21037/jtd.2020.01.43
DO - https://doi.org/10.21037/jtd.2020.01.43
M3 - Article
C2 - 32274092
SN - 2072-1439
VL - 12
SP - 258
EP - 263
JO - Journal of thoracic disease
JF - Journal of thoracic disease
IS - 3
ER -