TY - JOUR
T1 - Expression of cVg1 mRNA during chicken embryonic development
AU - Somi, Semir
AU - Houweling, Arjan C.
AU - Moorman, Antoon F. M.
AU - van den Hoff, Maurice J. B.
AU - Buffing, Anita A.M.
PY - 2003/7
Y1 - 2003/7
N2 - Using degenerated PCR-primers to identify known and novel BMPs that are expressed in the developing chicken heart, we identified not only BMP2, -4, and -7 mRNA, but also the TGFbeta superfamily member cVg1. The expression pattern of cVg1 mRNA was determined during chicken development from HH4 to HH44. In early developmental stages, cVg1 mRNA is expressed in the primitive streak, paraxial mesoderm, developing somites, and developing neural tube. Subsequently, cVg1 mRNA is expressed in the developing central and peripheral nervous system, retina, auditory vesicle, notochord, lung alveoli, and olfactory mucosa. In the heart, cVg1 is initially expressed through the linear heart tube, but becomes restricted to the forming chamber myocardium, in an expression domain similar to that of atrial natriuretic factor (ANF) mRNA
AB - Using degenerated PCR-primers to identify known and novel BMPs that are expressed in the developing chicken heart, we identified not only BMP2, -4, and -7 mRNA, but also the TGFbeta superfamily member cVg1. The expression pattern of cVg1 mRNA was determined during chicken development from HH4 to HH44. In early developmental stages, cVg1 mRNA is expressed in the primitive streak, paraxial mesoderm, developing somites, and developing neural tube. Subsequently, cVg1 mRNA is expressed in the developing central and peripheral nervous system, retina, auditory vesicle, notochord, lung alveoli, and olfactory mucosa. In the heart, cVg1 is initially expressed through the linear heart tube, but becomes restricted to the forming chamber myocardium, in an expression domain similar to that of atrial natriuretic factor (ANF) mRNA
KW - Atrial natriuretic factor
KW - Heart
KW - Nervous system
KW - Otic vesicle
KW - Retina
KW - TGFβ-superfamily
KW - cVg1
UR - http://www.scopus.com/inward/record.url?scp=0242643505&partnerID=8YFLogxK
U2 - https://doi.org/10.1002/ar.a.10070
DO - https://doi.org/10.1002/ar.a.10070
M3 - Article
C2 - 12808645
SN - 1552-4884
VL - 273
SP - 603
EP - 608
JO - Anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology
JF - Anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology
IS - 1
ER -