Extracellular vesicles in physiological and pathological conditions

Yuana Yuana; Auguste Sturk; Rienk Nieuwland

doi:https://doi.org/10.1016/j.blre.2012.12.002

Extracellular vesicles in physiological and pathological conditions

Yuana Yuana, Auguste Sturk, Rienk Nieuwland

Research output: Contribution to journal › Review article › Academic › peer-review

406 Citations (Scopus)

Abstract

Body fluids contain surprising numbers of cell-derived vesicles which are now thought to contribute to both physiology and pathology. Tools to improve the detection of vesicles are being developed and clinical applications using vesicles for diagnosis, prognosis, and therapy are under investigation. The increased understanding why cells release vesicles, how vesicles play a role in intercellular communication, and how vesicles may concurrently contribute to cellular homeostasis and host defense, reveals a very complex and sophisticated contribution of vesicles to health and disease

Original language	English
Pages (from-to)	31-39
Journal	Blood Reviews
Volume	27
Issue number	1
DOIs	https://doi.org/10.1016/j.blre.2012.12.002
Publication status	Published - 2013

Access to Document

https://doi.org/10.1016/j.blre.2012.12.002

Cite this

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title = "Extracellular vesicles in physiological and pathological conditions",

abstract = "Body fluids contain surprising numbers of cell-derived vesicles which are now thought to contribute to both physiology and pathology. Tools to improve the detection of vesicles are being developed and clinical applications using vesicles for diagnosis, prognosis, and therapy are under investigation. The increased understanding why cells release vesicles, how vesicles play a role in intercellular communication, and how vesicles may concurrently contribute to cellular homeostasis and host defense, reveals a very complex and sophisticated contribution of vesicles to health and disease",

author = "Yuana Yuana and Auguste Sturk and Rienk Nieuwland",

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AU - Sturk, Auguste

AU - Nieuwland, Rienk

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AB - Body fluids contain surprising numbers of cell-derived vesicles which are now thought to contribute to both physiology and pathology. Tools to improve the detection of vesicles are being developed and clinical applications using vesicles for diagnosis, prognosis, and therapy are under investigation. The increased understanding why cells release vesicles, how vesicles play a role in intercellular communication, and how vesicles may concurrently contribute to cellular homeostasis and host defense, reveals a very complex and sophisticated contribution of vesicles to health and disease

U2 - https://doi.org/10.1016/j.blre.2012.12.002

DO - https://doi.org/10.1016/j.blre.2012.12.002

M3 - Review article

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SN - 0268-960X

VL - 27

SP - 31

EP - 39

JO - Blood Reviews

JF - Blood Reviews

IS - 1

ER -