TY - JOUR
T1 - Facial Skin Lesions in Children Caused by Nontuberculous Mycobacteria
AU - Lindeboom, Jerome A.
PY - 2016
Y1 - 2016
N2 - Nontuberculous mycobacteria rarely cause facial skin lesions in immunocompetent children. I describe the clinical features and treatment of nontuberculous mycobacteria facial lesions. The diagnosis of a facial nontuberculous mycobacteria infection was established using polymerase chain reaction. Of 286 children with confirmed nontuberculous mycobacteria infection, 14 (4.9%; median age 50 mos, range 9-156 mos; 5 [36%] male, 9 [64%] female) had nontuberculous mycobacteria facial skin lesions. Six (43%) had lesions on the cheek and five (36%) in the medial eye corner. Polymerase chain reaction results confirmed the presence of Mycobacterium haemophilum in eight patients (57%) and Mycobacterium avium in six patients (43%). The facial lesions were treated using a combination of clarithromycin and rifabutin for 12 weeks, with a median healing time of 4 months. Nontuberculous mycobacteria facial lesions are rare in immunocompetent children. The diagnosis requires a high index of suspicion. Nonsurgical treatment is preferable, because surgical excision of the cutaneous lesions might lead to undesirable visible facial scars
AB - Nontuberculous mycobacteria rarely cause facial skin lesions in immunocompetent children. I describe the clinical features and treatment of nontuberculous mycobacteria facial lesions. The diagnosis of a facial nontuberculous mycobacteria infection was established using polymerase chain reaction. Of 286 children with confirmed nontuberculous mycobacteria infection, 14 (4.9%; median age 50 mos, range 9-156 mos; 5 [36%] male, 9 [64%] female) had nontuberculous mycobacteria facial skin lesions. Six (43%) had lesions on the cheek and five (36%) in the medial eye corner. Polymerase chain reaction results confirmed the presence of Mycobacterium haemophilum in eight patients (57%) and Mycobacterium avium in six patients (43%). The facial lesions were treated using a combination of clarithromycin and rifabutin for 12 weeks, with a median healing time of 4 months. Nontuberculous mycobacteria facial lesions are rare in immunocompetent children. The diagnosis requires a high index of suspicion. Nonsurgical treatment is preferable, because surgical excision of the cutaneous lesions might lead to undesirable visible facial scars
U2 - https://doi.org/10.1111/pde.12755
DO - https://doi.org/10.1111/pde.12755
M3 - Article
C2 - 26823205
SN - 0736-8046
VL - 33
SP - 196
EP - 199
JO - Pediatric dermatology
JF - Pediatric dermatology
IS - 2
ER -