Feasibility of Using Source-Level Brain Computer Interface for People with Multiple Sclerosis

John S. Russo; Mukul Chodhary; Myrte Strik; Thomas A. Shiels; Chin-Hsuan Sophie Lin; Sam E. John; David B. Grayden

doi:10.1109/EMBC40787.2023.10340364

Feasibility of Using Source-Level Brain Computer Interface for People with Multiple Sclerosis

John S. Russo, Mukul Chodhary, Myrte Strik, Thomas A. Shiels, Chin-Hsuan Sophie Lin, Sam E. John, David B. Grayden

Anatomy and neurosciences (VUmc)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Abstract

This work evaluates the feasibility of using a source level Brain-Computer Interface (BCI) for people with Multiple Sclerosis (MS). Data used was previously collected EEG of eight participants (one participant with MS and seven neurotypical participants) who performed imagined movement of the right and left hand. Equivalent current dipole cluster fitting was used to assess related brain activity at the source level and assessed using dipole location and power spectrum analysis. Dipole clusters were resolved within the motor cortices with some notable spatial difference between the MS and control participants. Neural sources that generate motor imagery originated from similar motor areas in the participant with MS compared to the neurotypical participants. Power spectral analysis indicated a reduced level of alpha power in the participant with MS during imagery tasks compared to neurotypical participants. Power in the beta band may be used to distinguish between left and right imagined movement for users with MS in BCI applications.Clinical Relevance - This paper demonstrates the cortical areas activated during imagined BCI-type tasks in a participant with Multiple Sclerosis (MS), and is a proof of concept for translating BCI research to potential users with MS.

Original language	English
Title of host publication	2023 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023 - Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9798350324471
DOIs	https://doi.org/10.1109/EMBC40787.2023.10340364
Publication status	Published - 2023
Event	45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023 - Sydney, Australia Duration: 24 Jul 2023 → 27 Jul 2023

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

Conference

Conference	45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023
Country/Territory	Australia
City	Sydney
Period	24/07/2023 → 27/07/2023

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10.1109/EMBC40787.2023.10340364

Cite this

Russo, J. S., Chodhary, M., Strik, M., Shiels, T. A., Lin, C.-H. S., John, S. E., & Grayden, D. B. (2023). Feasibility of Using Source-Level Brain Computer Interface for People with Multiple Sclerosis. In 2023 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023 - Proceedings (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC40787.2023.10340364

Russo, John S. ; Chodhary, Mukul ; Strik, Myrte et al. / Feasibility of Using Source-Level Brain Computer Interface for People with Multiple Sclerosis. 2023 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2023. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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title = "Feasibility of Using Source-Level Brain Computer Interface for People with Multiple Sclerosis",

abstract = "This work evaluates the feasibility of using a source level Brain-Computer Interface (BCI) for people with Multiple Sclerosis (MS). Data used was previously collected EEG of eight participants (one participant with MS and seven neurotypical participants) who performed imagined movement of the right and left hand. Equivalent current dipole cluster fitting was used to assess related brain activity at the source level and assessed using dipole location and power spectrum analysis. Dipole clusters were resolved within the motor cortices with some notable spatial difference between the MS and control participants. Neural sources that generate motor imagery originated from similar motor areas in the participant with MS compared to the neurotypical participants. Power spectral analysis indicated a reduced level of alpha power in the participant with MS during imagery tasks compared to neurotypical participants. Power in the beta band may be used to distinguish between left and right imagined movement for users with MS in BCI applications.Clinical Relevance - This paper demonstrates the cortical areas activated during imagined BCI-type tasks in a participant with Multiple Sclerosis (MS), and is a proof of concept for translating BCI research to potential users with MS.",

author = "Russo, {John S.} and Mukul Chodhary and Myrte Strik and Shiels, {Thomas A.} and Lin, {Chin-Hsuan Sophie} and John, {Sam E.} and Grayden, {David B.}",

year = "2023",

doi = "10.1109/EMBC40787.2023.10340364",

language = "English",

series = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

booktitle = "2023 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023 - Proceedings",

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note = "45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023 ; Conference date: 24-07-2023 Through 27-07-2023",

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Russo, JS, Chodhary, M, Strik, M, Shiels, TA, Lin, C-HS, John, SE & Grayden, DB 2023, Feasibility of Using Source-Level Brain Computer Interface for People with Multiple Sclerosis. in 2023 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023 - Proceedings. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers Inc., 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023, Sydney, Australia, 24/07/2023. https://doi.org/10.1109/EMBC40787.2023.10340364

Feasibility of Using Source-Level Brain Computer Interface for People with Multiple Sclerosis. / Russo, John S.; Chodhary, Mukul; Strik, Myrte et al.
2023 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2023. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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AU - Russo, John S.

AU - Chodhary, Mukul

AU - Strik, Myrte

AU - Shiels, Thomas A.

AU - Lin, Chin-Hsuan Sophie

AU - John, Sam E.

AU - Grayden, David B.

PY - 2023

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N2 - This work evaluates the feasibility of using a source level Brain-Computer Interface (BCI) for people with Multiple Sclerosis (MS). Data used was previously collected EEG of eight participants (one participant with MS and seven neurotypical participants) who performed imagined movement of the right and left hand. Equivalent current dipole cluster fitting was used to assess related brain activity at the source level and assessed using dipole location and power spectrum analysis. Dipole clusters were resolved within the motor cortices with some notable spatial difference between the MS and control participants. Neural sources that generate motor imagery originated from similar motor areas in the participant with MS compared to the neurotypical participants. Power spectral analysis indicated a reduced level of alpha power in the participant with MS during imagery tasks compared to neurotypical participants. Power in the beta band may be used to distinguish between left and right imagined movement for users with MS in BCI applications.Clinical Relevance - This paper demonstrates the cortical areas activated during imagined BCI-type tasks in a participant with Multiple Sclerosis (MS), and is a proof of concept for translating BCI research to potential users with MS.

AB - This work evaluates the feasibility of using a source level Brain-Computer Interface (BCI) for people with Multiple Sclerosis (MS). Data used was previously collected EEG of eight participants (one participant with MS and seven neurotypical participants) who performed imagined movement of the right and left hand. Equivalent current dipole cluster fitting was used to assess related brain activity at the source level and assessed using dipole location and power spectrum analysis. Dipole clusters were resolved within the motor cortices with some notable spatial difference between the MS and control participants. Neural sources that generate motor imagery originated from similar motor areas in the participant with MS compared to the neurotypical participants. Power spectral analysis indicated a reduced level of alpha power in the participant with MS during imagery tasks compared to neurotypical participants. Power in the beta band may be used to distinguish between left and right imagined movement for users with MS in BCI applications.Clinical Relevance - This paper demonstrates the cortical areas activated during imagined BCI-type tasks in a participant with Multiple Sclerosis (MS), and is a proof of concept for translating BCI research to potential users with MS.

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DO - 10.1109/EMBC40787.2023.10340364

M3 - Conference contribution

C2 - 38083693

T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

BT - 2023 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023 - Proceedings

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023

Y2 - 24 July 2023 through 27 July 2023

ER -

Russo JS, Chodhary M, Strik M, Shiels TA, Lin CHS, John SE et al. Feasibility of Using Source-Level Brain Computer Interface for People with Multiple Sclerosis. In 2023 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Conference, EMBC 2023 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2023. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC40787.2023.10340364

Feasibility of Using Source-Level Brain Computer Interface for People with Multiple Sclerosis

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