Fecal microbiota transplantation: Therapeutic potential for a multitude of diseases beyond Clostridium difficile

Guido J. Bakker, Max Nieuwdorp

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Abstract

The human intestinal tract contains trillions of bacteria, collectively called the gut microbiota. The majority of bacteria belong to the Gram-negative phyla Bacteroidetes and Proteobacteria and the Gram-positive phyla Firmicutes and Actinobacteria (1). In humans, the diversity of the gut microbiota and the abundance of species increase rapidly after birth and, after 2 to 4 years, remain relatively stable throughout adult life (2). Nevertheless, shifts in gut microbiota composition may occur, especially after use of antibiotics. Even a short course of antibiotics can result in perturbations that last for several years (3, 4).
Original languageEnglish
Title of host publicationBugs as Drugs: Therapeutic Microbes for Prevention and Treatment of Disease
PublisherWiley
Pages291-308
ISBN (Electronic)9781683670803
ISBN (Print)9781555819699
DOIs
Publication statusPublished - 1 Jan 2018

Publication series

NameBugs as Drugs: Therapeutic Microbes for Prevention and Treatment of Disease

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