Fecestransplantatie voor kinderen met recidiverende C. difficile-infecties

Rogier E. Ooijevaar; Tessel M. van Rossen; Christina M. J. E. Vandenbroucke-Grauls; Andries E. Budding; C. M. F. Kneepkens; Tim G. J. de Meij

Fecestransplantatie voor kinderen met recidiverende C. difficile-infecties

Translated title of the contribution: Fecal microbiota transplantation for children with recurrent C. difficile infections

Rogier E. Ooijevaar, Tessel M. van Rossen, Christina M. J. E. Vandenbroucke-Grauls, Andries E. Budding, C. M. F. Kneepkens, Tim G. J. de Meij

Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Scopus)

Abstract

BACKGROUND: Clostridioides difficile infection is a relatively rare cause of diarrhoea in children, but there are frequent recurrences when it occurs, despite targeted antibiotic treatment. CASE DESCRIPTIONS: A 2-year-old boy with concomitant motility disorder and a 14-year-old girl with Down syndrome experienced several infections with C. difficile, respectively after the use of antibiotics for otitis media and extended use of antibiotics in addition to chemotherapy. Both were treated successfully with faecal transplants. CONCLUSION: Clostridioides difficile infections occur in children, mainly after extended use of antibiotics or when the immune system is impaired. In case of recurring C. difficile infections, children can be treated safely and effectively with faecal transplants.

Translated title of the contribution	Fecal microbiota transplantation for children with recurrent C. difficile infections
Original language	Dutch
Article number	D3739
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	163
Issue number	31
Publication status	Published - 1 Jan 2019

Cite this

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title = "Fecestransplantatie voor kinderen met recidiverende C. difficile-infecties",

abstract = "BACKGROUND: Clostridioides difficile infection is a relatively rare cause of diarrhoea in children, but there are frequent recurrences when it occurs, despite targeted antibiotic treatment. CASE DESCRIPTIONS: A 2-year-old boy with concomitant motility disorder and a 14-year-old girl with Down syndrome experienced several infections with C. difficile, respectively after the use of antibiotics for otitis media and extended use of antibiotics in addition to chemotherapy. Both were treated successfully with faecal transplants. CONCLUSION: Clostridioides difficile infections occur in children, mainly after extended use of antibiotics or when the immune system is impaired. In case of recurring C. difficile infections, children can be treated safely and effectively with faecal transplants.",

author = "Ooijevaar, {Rogier E.} and {van Rossen}, {Tessel M.} and Vandenbroucke-Grauls, {Christina M. J. E.} and Budding, {Andries E.} and Kneepkens, {C. M. F.} and {de Meij}, {Tim G. J.}",

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language = "Dutch",

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journal = "Nederlands Tijdschrift voor Geneeskunde",

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T1 - Fecestransplantatie voor kinderen met recidiverende C. difficile-infecties

AU - Ooijevaar, Rogier E.

AU - van Rossen, Tessel M.

AU - Vandenbroucke-Grauls, Christina M. J. E.

AU - Budding, Andries E.

AU - Kneepkens, C. M. F.

AU - de Meij, Tim G. J.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - BACKGROUND: Clostridioides difficile infection is a relatively rare cause of diarrhoea in children, but there are frequent recurrences when it occurs, despite targeted antibiotic treatment. CASE DESCRIPTIONS: A 2-year-old boy with concomitant motility disorder and a 14-year-old girl with Down syndrome experienced several infections with C. difficile, respectively after the use of antibiotics for otitis media and extended use of antibiotics in addition to chemotherapy. Both were treated successfully with faecal transplants. CONCLUSION: Clostridioides difficile infections occur in children, mainly after extended use of antibiotics or when the immune system is impaired. In case of recurring C. difficile infections, children can be treated safely and effectively with faecal transplants.

AB - BACKGROUND: Clostridioides difficile infection is a relatively rare cause of diarrhoea in children, but there are frequent recurrences when it occurs, despite targeted antibiotic treatment. CASE DESCRIPTIONS: A 2-year-old boy with concomitant motility disorder and a 14-year-old girl with Down syndrome experienced several infections with C. difficile, respectively after the use of antibiotics for otitis media and extended use of antibiotics in addition to chemotherapy. Both were treated successfully with faecal transplants. CONCLUSION: Clostridioides difficile infections occur in children, mainly after extended use of antibiotics or when the immune system is impaired. In case of recurring C. difficile infections, children can be treated safely and effectively with faecal transplants.

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UR - https://www.ncbi.nlm.nih.gov/pubmed/31361420

M3 - Article

C2 - 31361420

SN - 0028-2162

VL - 163

JO - Nederlands Tijdschrift voor Geneeskunde

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IS - 31

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ER -

Fecestransplantatie voor kinderen met recidiverende C. difficile-infecties

Abstract

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