First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors

C. W. Menke; Carlos Gomez-Roca; Carla van Herpen; Andrew L. Coveler; Devalingam Mahalingam; Henk M. W. Verheul; Winette T. A. van der Graaf; Randolph Christen; Dominik Ruettinger; Stefan Weigand; Michael A. Cannarile; Florian Heil; Michael Brewster; Antje-Christine Walz; Tapan K. Nayak; Ernesto Guarin; Valerie Meresse; Christophe Le Tourneau

doi:https://doi.org/10.18632/oncotarget.11098

First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors

C. W. Menke, Carlos Gomez-Roca, Carla van Herpen, Andrew L. Coveler, Devalingam Mahalingam, Henk M. W. Verheul, Winette T. A. van der Graaf, Randolph Christen, Dominik Ruettinger, Stefan Weigand, Michael A. Cannarile, Florian Heil, Michael Brewster, Antje-Christine Walz, Tapan K. Nayak, Ernesto Guarin, Valerie Meresse, Christophe Le Tourneau

Medical oncology (VUmc)

Research output: Contribution to journal › Article › Academic › peer-review

86 Citations (Scopus)

Original language	English
Pages (from-to)	80046-80058
Journal	Oncotarget
Volume	7
Issue number	48
DOIs	https://doi.org/10.18632/oncotarget.11098
Publication status	Published - 29 Nov 2016

Keywords

RG7356
advanced CD44-expressing solid malignancies
advanced solid tumors
anti-CD44 humanized antibody
phase I trial

Access to Document

https://doi.org/10.18632/oncotarget.11098

Cite this

Menke, C. W., Gomez-Roca, C., van Herpen, C., Coveler, A. L., Mahalingam, D., Verheul, H. M. W., van der Graaf, W. T. A., Christen, R., Ruettinger, D., Weigand, S., Cannarile, M. A., Heil, F., Brewster, M., Walz, A.-C., Nayak, T. K., Guarin, E., Meresse, V., & Le Tourneau, C. (2016). First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors. Oncotarget, 7(48), 80046-80058. https://doi.org/10.18632/oncotarget.11098

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title = "First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors",

keywords = "RG7356, advanced CD44-expressing solid malignancies, advanced solid tumors, anti-CD44 humanized antibody, phase I trial",

author = "Menke, {C. W.} and Carlos Gomez-Roca and {van Herpen}, Carla and Coveler, {Andrew L.} and Devalingam Mahalingam and Verheul, {Henk M. W.} and {van der Graaf}, {Winette T. A.} and Randolph Christen and Dominik Ruettinger and Stefan Weigand and Cannarile, {Michael A.} and Florian Heil and Michael Brewster and Antje-Christine Walz and Nayak, {Tapan K.} and Ernesto Guarin and Valerie Meresse and {Le Tourneau}, Christophe",

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Menke, CW, Gomez-Roca, C, van Herpen, C, Coveler, AL, Mahalingam, D, Verheul, HMW, van der Graaf, WTA, Christen, R, Ruettinger, D, Weigand, S, Cannarile, MA, Heil, F, Brewster, M, Walz, A-C, Nayak, TK, Guarin, E, Meresse, V & Le Tourneau, C 2016, 'First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors', Oncotarget, vol. 7, no. 48, pp. 80046-80058. https://doi.org/10.18632/oncotarget.11098

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T1 - First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors

AU - Menke, C. W.

AU - Gomez-Roca, Carlos

AU - van Herpen, Carla

AU - Coveler, Andrew L.

AU - Mahalingam, Devalingam

AU - Verheul, Henk M. W.

AU - van der Graaf, Winette T. A.

AU - Christen, Randolph

AU - Ruettinger, Dominik

AU - Weigand, Stefan

AU - Cannarile, Michael A.

AU - Heil, Florian

AU - Brewster, Michael

AU - Walz, Antje-Christine

AU - Nayak, Tapan K.

AU - Guarin, Ernesto

AU - Meresse, Valerie

AU - Le Tourneau, Christophe

PY - 2016/11/29

Y1 - 2016/11/29

KW - RG7356

KW - advanced CD44-expressing solid malignancies

KW - advanced solid tumors

KW - anti-CD44 humanized antibody

KW - phase I trial

U2 - https://doi.org/10.18632/oncotarget.11098

DO - https://doi.org/10.18632/oncotarget.11098

M3 - Article

C2 - 27507056

SN - 1949-2553

VL - 7

SP - 80046

EP - 80058

JO - Oncotarget

JF - Oncotarget

IS - 48

ER -