TY - JOUR
T1 - First report of the use of long-tapered sirolimus-eluting coronary stent for the treatment of chronic total occlusions with the hybrid algorithm
AU - Zivelonghi, Carlo
AU - van Kuijk, Jan P.
AU - Nijenhuis, Vincent
AU - Poletti, Enrico
AU - Suttorp, Maarten J.
AU - van der Heyden, Jan A. S.
AU - Eefting, Frank D.
AU - Rensing, Benno J.
AU - ten Berg, Jurrien M.
AU - Azzalini, Lorenzo
AU - van den Brink, Floris S.
AU - Ribichini, Flavio
AU - Colombo, Antonio
AU - Henriques, José P. S.
AU - Agostoni, Pierfrancesco
PY - 2018
Y1 - 2018
N2 - Coronary chronic total occlusions (CTO) usually coexist with diffusely diseased coronary segments proximal and/or distal to the CTO segment. During percutaneous treatment of CTO, multiple overlapping stents are often needed to treat these long lesions. Aim of this study is to report the first use of long, tapered coronary sirolimus-eluting stents (SES) in this setting. This is a retrospective analysis of 100 consecutive patients undergoing CTO recanalization following the hybrid algorithm. Procedural success rate was 89% (11 failures). Among the successful cases, "conventional" drug-eluting stents(DES) were used in 40(44.9%) patients, while in 49(55%) patients long-tapered SES were attempted with a success rate of 98% (1 cross-over to regular stents). Total stent length in the long-tapered DES group was higher compared to the "conventional" stenting group (76 ± 28 mm vs 46 ± 22 mm, P < .001), with a similar total number of stent (1.6 ± 0.8 vs 1.9 ± 0.8). At quantitative coronary analysis, proximal and distal segment involvement was more extended in patients undergoing long-tapered stenting, with longer overall lesion length. No differences in periprocedural complications and clinical outcomes at a mean follow-up of 303 ± 179 days were observed. The use of long tapered coronary DES is technically feasible and safe for the percutaneous treatment of CTOs, especially for patients presenting with long lesions
AB - Coronary chronic total occlusions (CTO) usually coexist with diffusely diseased coronary segments proximal and/or distal to the CTO segment. During percutaneous treatment of CTO, multiple overlapping stents are often needed to treat these long lesions. Aim of this study is to report the first use of long, tapered coronary sirolimus-eluting stents (SES) in this setting. This is a retrospective analysis of 100 consecutive patients undergoing CTO recanalization following the hybrid algorithm. Procedural success rate was 89% (11 failures). Among the successful cases, "conventional" drug-eluting stents(DES) were used in 40(44.9%) patients, while in 49(55%) patients long-tapered SES were attempted with a success rate of 98% (1 cross-over to regular stents). Total stent length in the long-tapered DES group was higher compared to the "conventional" stenting group (76 ± 28 mm vs 46 ± 22 mm, P < .001), with a similar total number of stent (1.6 ± 0.8 vs 1.9 ± 0.8). At quantitative coronary analysis, proximal and distal segment involvement was more extended in patients undergoing long-tapered stenting, with longer overall lesion length. No differences in periprocedural complications and clinical outcomes at a mean follow-up of 303 ± 179 days were observed. The use of long tapered coronary DES is technically feasible and safe for the percutaneous treatment of CTOs, especially for patients presenting with long lesions
U2 - https://doi.org/10.1002/ccd.27539
DO - https://doi.org/10.1002/ccd.27539
M3 - Article
C2 - 29411523
SN - 1522-1946
VL - 92
SP - E299-E307
JO - Catheterization and cardiovascular interventions
JF - Catheterization and cardiovascular interventions
IS - 5
ER -