Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

Anna Wojtuszkiewicz; Shachar Raz; Michal Stark; Yehuda G. Assaraf; Gerrit Jansen; Godefridus J. Peters; Edwin Sonneveld; Gertjan J. L. Kaspers; Jacqueline Cloos

doi:https://doi.org/10.1002/ijc.29919

Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

Anna Wojtuszkiewicz, Shachar Raz, Michal Stark, Yehuda G. Assaraf, Gerrit Jansen, Godefridus J. Peters, Edwin Sonneveld, Gertjan J. L. Kaspers, Jacqueline Cloos

Research output: Contribution to journal › Article › Academic › peer-review

34 Citations (Scopus)

Original language	English
Pages (from-to)	1645-1656
Journal	International journal of cancer
Volume	138
Issue number	7
DOIs	https://doi.org/10.1002/ijc.29919
Publication status	Published - 1 Apr 2016

Keywords

acute lymphoblastic leukemia
alternative splicing
drug resistance
folylpolyglutamate synthetase
methotrexate

Access to Document

https://doi.org/10.1002/ijc.29919

Cite this

Wojtuszkiewicz, A., Raz, S., Stark, M., Assaraf, Y. G., Jansen, G., Peters, G. J., Sonneveld, E., Kaspers, G. J. L., & Cloos, J. (2016). Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance. International journal of cancer, 138(7), 1645-1656. https://doi.org/10.1002/ijc.29919

@article{22251cecdd9842cb82eee4c965ab2063,

title = "Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance",

keywords = "acute lymphoblastic leukemia, alternative splicing, drug resistance, folylpolyglutamate synthetase, methotrexate",

author = "Anna Wojtuszkiewicz and Shachar Raz and Michal Stark and Assaraf, {Yehuda G.} and Gerrit Jansen and Peters, {Godefridus J.} and Edwin Sonneveld and Kaspers, {Gertjan J. L.} and Jacqueline Cloos",

year = "2016",

month = apr,

day = "1",

doi = "https://doi.org/10.1002/ijc.29919",

language = "English",

volume = "138",

pages = "1645--1656",

journal = "International journal of cancer",

issn = "0020-7136",

publisher = "International Union Against Cancer",

number = "7",

}

Wojtuszkiewicz, A, Raz, S, Stark, M, Assaraf, YG, Jansen, G , Peters, GJ, Sonneveld, E, Kaspers, GJL & Cloos, J 2016, 'Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance', International journal of cancer, vol. 138, no. 7, pp. 1645-1656. https://doi.org/10.1002/ijc.29919

Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance. / Wojtuszkiewicz, Anna; Raz, Shachar; Stark, Michal et al.
In: International journal of cancer, Vol. 138, No. 7, 01.04.2016, p. 1645-1656.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

AU - Wojtuszkiewicz, Anna

AU - Raz, Shachar

AU - Stark, Michal

AU - Assaraf, Yehuda G.

AU - Jansen, Gerrit

AU - Peters, Godefridus J.

AU - Sonneveld, Edwin

AU - Kaspers, Gertjan J. L.

AU - Cloos, Jacqueline

PY - 2016/4/1

Y1 - 2016/4/1

KW - acute lymphoblastic leukemia

KW - alternative splicing

KW - drug resistance

KW - folylpolyglutamate synthetase

KW - methotrexate

U2 - https://doi.org/10.1002/ijc.29919

DO - https://doi.org/10.1002/ijc.29919

M3 - Article

C2 - 26547381

SN - 0020-7136

VL - 138

SP - 1645

EP - 1656

JO - International journal of cancer

JF - International journal of cancer

IS - 7

ER -