Gadolinium: Een uitlokkende factor van nefrogene systemische fibrose?

Translated title of the contribution: Gadolinium: A provoking factor of nephrogenic systemic fibrosis?

S. M. Franken, M. Vervloet, Th M. Starink, T. J. Stoof

Research output: Contribution to journalArticleAcademicpeer-review


A 69-year-old female haemodialysis patient developed a sclerotic skin on the legs with pruritus. Two weeks before she underwent MRI scanning with a gadolinium containing contrast agent. She was diagnosed with nephrogenic systemic fibrosis (NSF). NSF is a progressive disease with significant morbidity and mortality. It is most likely caused by gadolinium containing contrast agents used in imaging studies (MRI/MRA). The disease occurs almost exclusively in patients with strongly diminished renal function, in whom the contrast agent is not eliminated fast enough and gadolinium is deposited in the skin.

Translated title of the contributionGadolinium: A provoking factor of nephrogenic systemic fibrosis?
Original languageDutch
Pages (from-to)306-308
Number of pages3
JournalNederlands Tijdschrift voor Dermatologie en Venereologie
Issue number8
Publication statusPublished - 1 Oct 2007


  • Gadolinium
  • Nephrogenic systemic fibrosis

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