TY - JOUR
T1 - Gain in lung function after weight reduction in severely obese children
AU - van de Griendt, E. J.
AU - van der Baan-Slootweg, O. H.
AU - van Essen-Zandvliet, E. E. M.
AU - van der Palen, J.
AU - Tamminga-Smeulders, C. L. J.
AU - Benninga, M. A.
AU - van Aalderen, W. M. C.
PY - 2012
Y1 - 2012
N2 - Aim The primary objective of this prospective cohort study was to determine the effect of weight loss on pulmonary function values in extremely obese children. Methods Obese children participated in a 26-week in-hospital or outpatient multidisciplinary treatment programme. Waist circumference was measured and pulmonary function tests were performed at enrolment and after 6 months. Results The data of 112 children were analysed. The children had a mean age of 14.4 (range 8.5-18.9) years and 62.5% were girls. The mean SD score-body mass index (SDS-BMI) was + 3.38 at baseline and + 2.91 after the intervention. Lung function improved significantly: functional vital capacity increased by 3.08% (95% CI 1.16% to 5.00%) of the predicted value, forced expiratory volume in 1 s (FEV1) by 2.91% (95% CI 1.11% to 4.71%) of the predicted value, total lung capacity by 2.27% (95% CI 1.16% to 5.00%) of the predicted value, and expiratory reserve volume (ERV) by 14.8% (95% CI 8.66% to 20.88%) of the predicted value. The increase in ERV correlated with the reduction in SDS-BMI and with the reduction in waist circumference. FEV1 did not correlate with the reduction in either SDS-BMI or waist circumference. Conclusions Weight loss in severely obese children correlated with an improvement in lung function, especially ERV. The improvement in ERV correlated with the decrease in SDS-BMI and waist circumference
AB - Aim The primary objective of this prospective cohort study was to determine the effect of weight loss on pulmonary function values in extremely obese children. Methods Obese children participated in a 26-week in-hospital or outpatient multidisciplinary treatment programme. Waist circumference was measured and pulmonary function tests were performed at enrolment and after 6 months. Results The data of 112 children were analysed. The children had a mean age of 14.4 (range 8.5-18.9) years and 62.5% were girls. The mean SD score-body mass index (SDS-BMI) was + 3.38 at baseline and + 2.91 after the intervention. Lung function improved significantly: functional vital capacity increased by 3.08% (95% CI 1.16% to 5.00%) of the predicted value, forced expiratory volume in 1 s (FEV1) by 2.91% (95% CI 1.11% to 4.71%) of the predicted value, total lung capacity by 2.27% (95% CI 1.16% to 5.00%) of the predicted value, and expiratory reserve volume (ERV) by 14.8% (95% CI 8.66% to 20.88%) of the predicted value. The increase in ERV correlated with the reduction in SDS-BMI and with the reduction in waist circumference. FEV1 did not correlate with the reduction in either SDS-BMI or waist circumference. Conclusions Weight loss in severely obese children correlated with an improvement in lung function, especially ERV. The improvement in ERV correlated with the decrease in SDS-BMI and waist circumference
U2 - https://doi.org/10.1136/archdischild-2011-301304
DO - https://doi.org/10.1136/archdischild-2011-301304
M3 - Article
C2 - 23076338
SN - 0003-9888
VL - 97
SP - 1039
EP - 1042
JO - Archives of disease in childhood
JF - Archives of disease in childhood
IS - 12
ER -