Gender differences in respiratory symptoms in 19-year-old adults born preterm

Elianne J. L. E. Vrijlandt; Jorrit Gerritsen; H. Marike Boezen; Eric J. Duiverman; E. T. M. Hille; C. H. de Groot; H. Kloosterboer-Boerrigter; A. L. den Ouden; A. Rijpstra; S. P. Verloove-Vanhorick; J. A. Vogelaar; J. H. Kok; A. Ilsen; M. van der Lans; W. J. C. Boelen-van der Loo; T. Lundqvist; H. S. A. Heymans; W. B. Geven; M. L. Duiverman; L. I. Geven; A. L. M. Mulder; A. Gerver; L. A. A. Kollée; L. Reijmers; R. Sonnemans; J. M. Wit; F. W. Dekker; M. J. J. Finken; N. Weisglas-Kuperus; M. G. Keijzer-Veen; A. J. van der Heijden; J. B. van Goudoever; M. M. van Weissenbruch; A. Cranendonk; H. A. Delemarre-van de Waal; L. de Groot; J. F. Samsom; L. S. de Vries; K. J. Rademaker; E. Moerman; M. Voogsgeerd; M. J. K. de Kleine; P. Andriessen; C. C. M. Dielissen-van Helvoirt; I. Mohamed; H. L. M. van Straaten; W. Baerts; G. W. Veneklaas Slots-Kloosterboer; E. M. J. Tuller-Pikkemaat; M. H. Ens-Dokkum; G. J. van Steenbrugge

doi:https://doi.org/10.1186/1465-9921-6-117

Gender differences in respiratory symptoms in 19-year-old adults born preterm

Elianne J. L. E. Vrijlandt, Jorrit Gerritsen, H. Marike Boezen, Eric J. Duiverman, E. T. M. Hille, C. H. de Groot, H. Kloosterboer-Boerrigter, A. L. den Ouden, A. Rijpstra, S. P. Verloove-Vanhorick, J. A. Vogelaar, J. H. Kok, A. Ilsen, M. van der Lans, W. J. C. Boelen-van der Loo, T. Lundqvist, H. S. A. Heymans, W. B. Geven, M. L. Duiverman, L. I. GevenA. L. M. Mulder, A. Gerver, L. A. A. Kollée, L. Reijmers, R. Sonnemans, J. M. Wit, F. W. Dekker, M. J. J. Finken, N. Weisglas-Kuperus, M. G. Keijzer-Veen, A. J. van der Heijden, J. B. van Goudoever, M. M. van Weissenbruch, A. Cranendonk, H. A. Delemarre-van de Waal, L. de Groot, J. F. Samsom, L. S. de Vries, K. J. Rademaker, E. Moerman, M. Voogsgeerd, M. J. K. de Kleine, P. Andriessen, C. C. M. Dielissen-van Helvoirt, I. Mohamed, H. L. M. van Straaten, W. Baerts, G. W. Veneklaas Slots-Kloosterboer, E. M. J. Tuller-Pikkemaat, M. H. Ens-Dokkum, G. J. van Steenbrugge

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Abstract

Objective: To study the prevalence of respiratory and atopic symptoms in (young) adults born prematurely, differences between those who did and did not develop Bronchopulmonary Disease (BPD) at neonatal age and differences in respiratory health between males and females. Methods: Design: Prospective cohort study. Setting: Nation wide follow-up study, the Netherlands. Participants: 690 adults (19 year old) born with a gestational age below 32 completed weeks and/or with a birth weight less than 1500g. Controls were Dutch participants of the European Community Respiratory Health Survey (ECRHS). Main outcome measures: Presence of wheeze, shortness of breath, asthma, hay fever and eczema using the ECRHS-questionnaire Results: The prevalence of doctor-diagnosed asthma was significantly higher in the ex-preterms than in the general population, whereas eczema and hay fever were significant lower. Women reported more symptoms than men. Preterm women vs controls: asthma 13% vs 5% (p<0.001); hay fever 8% vs 20% (p<0.001); eczema 10% vs 42% (p<0.001). Preterm men vs controls: asthma 9% vs 4% (p=0.007); hay fever 8% vs 17% (p=0.005); eczema 9% vs 31% (p<0.001) Preterm women reported more wheeze and shortness of breath during exercise (sob) than controls: wheeze 30% vs 22% (p=0.009); sob 27% vs 16% (p<0.001); 19-year-old women with BPD reported a higher prevalence of doctor diagnosed asthma compared to controls (24% vs 5% p <0.001) and shortness of breath during exercise (43% vs 16% p=0.008). The prevalence of reported symptoms by men with BPD were comparable with the controls. Conclusions: Our large follow-up study shows a higher prevalence of asthma, wheeze and shortness of breath in the prematurely born young adults. 19-year-old women reported more respiratory symptoms than men. Compared to the general population atopic diseases as hay fever and eczema were reported less often. © 2005 Vrijlandt et al., licensee BioMed Central Ltd.

Original language	English
Article number	117
Journal	Respiratory research
Volume	6
DOIs	https://doi.org/10.1186/1465-9921-6-117
Publication status	Published - 13 Oct 2005

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Vrijlandt, E. J. L. E., Gerritsen, J., Boezen, H. M., Duiverman, E. J., Hille, E. T. M., de Groot, C. H., Kloosterboer-Boerrigter, H., den Ouden, A. L., Rijpstra, A., Verloove-Vanhorick, S. P., Vogelaar, J. A., Kok, J. H., Ilsen, A., van der Lans, M., Boelen-van der Loo, W. J. C., Lundqvist, T., Heymans, H. S. A., Geven, W. B., Duiverman, M. L., ... van Steenbrugge, G. J. (2005). Gender differences in respiratory symptoms in 19-year-old adults born preterm. Respiratory research, 6, Article 117. https://doi.org/10.1186/1465-9921-6-117

@article{3b7099775ceb45ceaa39cc219cb2604b,

title = "Gender differences in respiratory symptoms in 19-year-old adults born preterm",

abstract = "Objective: To study the prevalence of respiratory and atopic symptoms in (young) adults born prematurely, differences between those who did and did not develop Bronchopulmonary Disease (BPD) at neonatal age and differences in respiratory health between males and females. Methods: Design: Prospective cohort study. Setting: Nation wide follow-up study, the Netherlands. Participants: 690 adults (19 year old) born with a gestational age below 32 completed weeks and/or with a birth weight less than 1500g. Controls were Dutch participants of the European Community Respiratory Health Survey (ECRHS). Main outcome measures: Presence of wheeze, shortness of breath, asthma, hay fever and eczema using the ECRHS-questionnaire Results: The prevalence of doctor-diagnosed asthma was significantly higher in the ex-preterms than in the general population, whereas eczema and hay fever were significant lower. Women reported more symptoms than men. Preterm women vs controls: asthma 13% vs 5% (p<0.001); hay fever 8% vs 20% (p<0.001); eczema 10% vs 42% (p<0.001). Preterm men vs controls: asthma 9% vs 4% (p=0.007); hay fever 8% vs 17% (p=0.005); eczema 9% vs 31% (p<0.001) Preterm women reported more wheeze and shortness of breath during exercise (sob) than controls: wheeze 30% vs 22% (p=0.009); sob 27% vs 16% (p<0.001); 19-year-old women with BPD reported a higher prevalence of doctor diagnosed asthma compared to controls (24% vs 5% p <0.001) and shortness of breath during exercise (43% vs 16% p=0.008). The prevalence of reported symptoms by men with BPD were comparable with the controls. Conclusions: Our large follow-up study shows a higher prevalence of asthma, wheeze and shortness of breath in the prematurely born young adults. 19-year-old women reported more respiratory symptoms than men. Compared to the general population atopic diseases as hay fever and eczema were reported less often. {\textcopyright} 2005 Vrijlandt et al., licensee BioMed Central Ltd.",

author = "Vrijlandt, {Elianne J. L. E.} and Jorrit Gerritsen and Boezen, {H. Marike} and Duiverman, {Eric J.} and Hille, {E. T. M.} and {de Groot}, {C. H.} and H. Kloosterboer-Boerrigter and {den Ouden}, {A. L.} and A. Rijpstra and Verloove-Vanhorick, {S. P.} and Vogelaar, {J. A.} and Kok, {J. H.} and A. Ilsen and {van der Lans}, M. and {Boelen-van der Loo}, {W. J. C.} and T. Lundqvist and Heymans, {H. S. A.} and Geven, {W. B.} and Duiverman, {M. L.} and Geven, {L. I.} and Mulder, {A. L. M.} and A. Gerver and Koll{\'e}e, {L. A. A.} and L. Reijmers and R. Sonnemans and Wit, {J. M.} and Dekker, {F. W.} and Finken, {M. J. J.} and N. Weisglas-Kuperus and Keijzer-Veen, {M. G.} and {van der Heijden}, {A. J.} and {van Goudoever}, {J. B.} and {van Weissenbruch}, {M. M.} and A. Cranendonk and {Delemarre-van de Waal}, {H. A.} and {de Groot}, L. and Samsom, {J. F.} and {de Vries}, {L. S.} and Rademaker, {K. J.} and E. Moerman and M. Voogsgeerd and {de Kleine}, {M. J. K.} and P. Andriessen and {Dielissen-van Helvoirt}, {C. C. M.} and I. Mohamed and {van Straaten}, {H. L. M.} and W. Baerts and {Veneklaas Slots-Kloosterboer}, {G. W.} and Tuller-Pikkemaat, {E. M. J.} and Ens-Dokkum, {M. H.} and {van Steenbrugge}, {G. J.}",

year = "2005",

month = oct,

day = "13",

doi = "https://doi.org/10.1186/1465-9921-6-117",

language = "English",

volume = "6",

journal = "Respiratory research",

issn = "1465-993X",

publisher = "BioMed Central",

}

Vrijlandt, EJLE, Gerritsen, J, Boezen, HM, Duiverman, EJ, Hille, ETM, de Groot, CH, Kloosterboer-Boerrigter, H, den Ouden, AL, Rijpstra, A, Verloove-Vanhorick, SP, Vogelaar, JA, Kok, JH, Ilsen, A, van der Lans, M, Boelen-van der Loo, WJC, Lundqvist, T, Heymans, HSA, Geven, WB, Duiverman, ML, Geven, LI, Mulder, ALM, Gerver, A, Kollée, LAA, Reijmers, L, Sonnemans, R, Wit, JM, Dekker, FW, Finken, MJJ, Weisglas-Kuperus, N, Keijzer-Veen, MG, van der Heijden, AJ, van Goudoever, JB, van Weissenbruch, MM, Cranendonk, A, Delemarre-van de Waal, HA, de Groot, L, Samsom, JF, de Vries, LS, Rademaker, KJ, Moerman, E, Voogsgeerd, M, de Kleine, MJK, Andriessen, P, Dielissen-van Helvoirt, CCM, Mohamed, I, van Straaten, HLM, Baerts, W, Veneklaas Slots-Kloosterboer, GW, Tuller-Pikkemaat, EMJ, Ens-Dokkum, MH & van Steenbrugge, GJ 2005, 'Gender differences in respiratory symptoms in 19-year-old adults born preterm', Respiratory research, vol. 6, 117. https://doi.org/10.1186/1465-9921-6-117

TY - JOUR

T1 - Gender differences in respiratory symptoms in 19-year-old adults born preterm

AU - Vrijlandt, Elianne J. L. E.

AU - Gerritsen, Jorrit

AU - Boezen, H. Marike

AU - Duiverman, Eric J.

AU - Hille, E. T. M.

AU - de Groot, C. H.

AU - Kloosterboer-Boerrigter, H.

AU - den Ouden, A. L.

AU - Rijpstra, A.

AU - Verloove-Vanhorick, S. P.

AU - Vogelaar, J. A.

AU - Kok, J. H.

AU - Ilsen, A.

AU - van der Lans, M.

AU - Boelen-van der Loo, W. J. C.

AU - Lundqvist, T.

AU - Heymans, H. S. A.

AU - Geven, W. B.

AU - Duiverman, M. L.

AU - Geven, L. I.

AU - Mulder, A. L. M.

AU - Gerver, A.

AU - Kollée, L. A. A.

AU - Reijmers, L.

AU - Sonnemans, R.

AU - Wit, J. M.

AU - Dekker, F. W.

AU - Finken, M. J. J.

AU - Weisglas-Kuperus, N.

AU - Keijzer-Veen, M. G.

AU - van der Heijden, A. J.

AU - van Goudoever, J. B.

AU - van Weissenbruch, M. M.

AU - Cranendonk, A.

AU - Delemarre-van de Waal, H. A.

AU - de Groot, L.

AU - Samsom, J. F.

AU - de Vries, L. S.

AU - Rademaker, K. J.

AU - Moerman, E.

AU - Voogsgeerd, M.

AU - de Kleine, M. J. K.

AU - Andriessen, P.

AU - Dielissen-van Helvoirt, C. C. M.

AU - Mohamed, I.

AU - van Straaten, H. L. M.

AU - Baerts, W.

AU - Veneklaas Slots-Kloosterboer, G. W.

AU - Tuller-Pikkemaat, E. M. J.

AU - Ens-Dokkum, M. H.

AU - van Steenbrugge, G. J.

PY - 2005/10/13

Y1 - 2005/10/13

N2 - Objective: To study the prevalence of respiratory and atopic symptoms in (young) adults born prematurely, differences between those who did and did not develop Bronchopulmonary Disease (BPD) at neonatal age and differences in respiratory health between males and females. Methods: Design: Prospective cohort study. Setting: Nation wide follow-up study, the Netherlands. Participants: 690 adults (19 year old) born with a gestational age below 32 completed weeks and/or with a birth weight less than 1500g. Controls were Dutch participants of the European Community Respiratory Health Survey (ECRHS). Main outcome measures: Presence of wheeze, shortness of breath, asthma, hay fever and eczema using the ECRHS-questionnaire Results: The prevalence of doctor-diagnosed asthma was significantly higher in the ex-preterms than in the general population, whereas eczema and hay fever were significant lower. Women reported more symptoms than men. Preterm women vs controls: asthma 13% vs 5% (p<0.001); hay fever 8% vs 20% (p<0.001); eczema 10% vs 42% (p<0.001). Preterm men vs controls: asthma 9% vs 4% (p=0.007); hay fever 8% vs 17% (p=0.005); eczema 9% vs 31% (p<0.001) Preterm women reported more wheeze and shortness of breath during exercise (sob) than controls: wheeze 30% vs 22% (p=0.009); sob 27% vs 16% (p<0.001); 19-year-old women with BPD reported a higher prevalence of doctor diagnosed asthma compared to controls (24% vs 5% p <0.001) and shortness of breath during exercise (43% vs 16% p=0.008). The prevalence of reported symptoms by men with BPD were comparable with the controls. Conclusions: Our large follow-up study shows a higher prevalence of asthma, wheeze and shortness of breath in the prematurely born young adults. 19-year-old women reported more respiratory symptoms than men. Compared to the general population atopic diseases as hay fever and eczema were reported less often. © 2005 Vrijlandt et al., licensee BioMed Central Ltd.

AB - Objective: To study the prevalence of respiratory and atopic symptoms in (young) adults born prematurely, differences between those who did and did not develop Bronchopulmonary Disease (BPD) at neonatal age and differences in respiratory health between males and females. Methods: Design: Prospective cohort study. Setting: Nation wide follow-up study, the Netherlands. Participants: 690 adults (19 year old) born with a gestational age below 32 completed weeks and/or with a birth weight less than 1500g. Controls were Dutch participants of the European Community Respiratory Health Survey (ECRHS). Main outcome measures: Presence of wheeze, shortness of breath, asthma, hay fever and eczema using the ECRHS-questionnaire Results: The prevalence of doctor-diagnosed asthma was significantly higher in the ex-preterms than in the general population, whereas eczema and hay fever were significant lower. Women reported more symptoms than men. Preterm women vs controls: asthma 13% vs 5% (p<0.001); hay fever 8% vs 20% (p<0.001); eczema 10% vs 42% (p<0.001). Preterm men vs controls: asthma 9% vs 4% (p=0.007); hay fever 8% vs 17% (p=0.005); eczema 9% vs 31% (p<0.001) Preterm women reported more wheeze and shortness of breath during exercise (sob) than controls: wheeze 30% vs 22% (p=0.009); sob 27% vs 16% (p<0.001); 19-year-old women with BPD reported a higher prevalence of doctor diagnosed asthma compared to controls (24% vs 5% p <0.001) and shortness of breath during exercise (43% vs 16% p=0.008). The prevalence of reported symptoms by men with BPD were comparable with the controls. Conclusions: Our large follow-up study shows a higher prevalence of asthma, wheeze and shortness of breath in the prematurely born young adults. 19-year-old women reported more respiratory symptoms than men. Compared to the general population atopic diseases as hay fever and eczema were reported less often. © 2005 Vrijlandt et al., licensee BioMed Central Ltd.

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UR - https://www.ncbi.nlm.nih.gov/pubmed/16223446

U2 - https://doi.org/10.1186/1465-9921-6-117

DO - https://doi.org/10.1186/1465-9921-6-117

M3 - Article

C2 - 16223446

SN - 1465-993X

VL - 6

JO - Respiratory research

JF - Respiratory research

M1 - 117

ER -

Gender differences in respiratory symptoms in 19-year-old adults born preterm

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