Generating a list of potentially important contextual factors covering randomized trials, cohorts, and measurement property studies: An OMERACT initiative

Max Weinbrecht-Mischkewitz, Midhat Kamal, Farwa Asim, Francis Guillemin, Niti Goel, Marieke Voshaar, Annelies Boonen, Dorthe Bang Berthelsen, Karine Toupin-April, Maria A. Lopez-Olivo, Victor S. Sloan, Maarten Boers, C. Allyson Jones, Irene van der Horst-Bruinsma, Aidan G. Cashin, Saurab Sharma, Amye Leong, Rieke Alten, Beverley Shea, Lyn MarchContextual Factors Working Group

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objectives: To generate candidates for contextual factors (CFs) for each CF type (i.e., Effect Modifying Contextual Factors (EM-CFs), Outcome Influencing Contextual Factors (OI-CFs), and Measurement Affecting Contextual Factors (MA-CFs)) considered important within rheumatology. Methods: We surveyed OMERACT working groups and conducted a Special Interest Group (SIG) session at the OMERACT 2023 meeting, where the results were reviewed, and additional CFs suggested. Results: The working groups suggested 44, 49, and 21 generic EM-CFs, OI-CFs, and MA-CFs, respectively. SIG participants added 49, 44, and 55 factors, respectively. Conclusion: Candidate CFs were identified, next step is a consensus-based set of endorsed (important) CFs.
Original languageEnglish
Article number152370
JournalSeminars in Arthritis and Rheumatism
Volume65
DOIs
Publication statusPublished - 1 Apr 2024

Keywords

  • Arthritis
  • Contextual factors
  • Effect modifiers
  • Measurement instruments
  • OMERACT
  • Prognostic factors
  • Rheumatology

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